1/ New analysis reveals a stark reality: 1 in 5 COVID-19 survivors still battle symptoms 3 years after severe infection. This meta-analysis of 11 studies highlights the profound, lasting effects on health and quality of life. #LongCovid #PostCovid
2/ The most common persistent symptoms include fatigue, sleep disturbances, and shortness of breath. These aren't just minor annoyances; they significantly impact daily living and long-term well-being. #ChronicIllness #HealthCrisis
3/ This research, published in the Journal of Medical Virology, evaluated data from over 142,000 patients across Europe, Asia, and Australia, predominantly focusing on those hospitalized in 2020. The numbers are sobering. #MedicalResearch #PublicHealth
4/ Beyond daily symptoms, the analysis found an increased risk of death at 3 years for hospitalized COVID-19 patients. Long COVID also contributed significantly to disability-adjusted life years (DALYs), showcasing a massive societal burden. #MortalityRisk #Disability
5/ Neurological, pulmonary, and cardiovascular issues were the most common long-term physiological clusters. Memory impairment, heart failure, and reduced lung function persist for many, underscoring the systemic nature of the disease. #Neurological #Pulmonary #Cardiovascular
6/ Risk factors for persistent symptoms include older age, severe infection, hospitalization, and underlying health conditions. This emphasizes that COVID-19 is not "just a flu" for a significant portion of the population. #RiskFactors #COVID19
7/ A critical missing piece? Data on how many Long COVID patients have been able to return to their original jobs after 3 years. This gap highlights the urgent need for more comprehensive research into the socioeconomic impact. #ReturnToWork #SocietalImpact
8/ The findings underscore the necessity of interdisciplinary care teams and integrating Long COVID management into routine healthcare. Public health campaigns are crucial to raise awareness and reduce stigma. #HealthcarePolicy #PatientCare
9/ Given the severe, long-term consequences, preventing infection and reducing viral exposure remains paramount. This means focusing on both environmental controls and personal protective measures. #PreventionIsKey #ViralProtection
10/ One vital step? Cleaning the air we breathe. Investing in air purification systems, especially with HEPA filters, can significantly reduce airborne viral particles in indoor spaces. Let's make clean air a priority! #AirPurifiers #IndoorAirQuality
11/ And for personal protection, especially in higher-risk environments, high-quality masks like N95s (or equivalent KN95/FFP2/3) are indispensable. They provide superior filtration, greatly reducing inhalation of airborne viruses. #N95Masks #MaskUp
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The evidence is clear: Long COVID is a significant and lasting health challenge. By embracing comprehensive care for survivors AND proactive prevention measures like air purification and N95 masking, we can better protect ourselves and our communities. #CleanAirNow
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H/T @scott_squires for his amazing poster collection!
1/ New science from bioRxiv (10.64898/2025.12.31.697156) shows that asthma isn't just a "reaction"—it's a fundamental destruction of our airway's molecular program. Our lungs are being physically rewritten by chronic exposure. 🧵👇 The #LeonardiEffect is very real!
2/ Crucially, the study highlights how T-cells become dysfunctional and drive permanent scarring (remodeling). But there's more: research from MedUni Wien confirms that SARS-CoV-2 infections cause long-term damage to our entire immune system. 🫁⚠️
3/ The Vienna study shows that even mild infections can inhibit T-cell memory and significantly reduce immune cells in the blood for over 10 months. This means your body has a harder time fighting off common infections like Influenza A, Staph, or VZV.
1/ Is SARS-CoV-2 more than just a respiratory virus? Emerging research is raising a chilling question: Could COVID-19 be an oncovirus? Recent studies suggest the virus may interfere with our body’s ability to prevent and fight cancer. Let’s dive into the science. 🧬👇 #Cancer
2/ A key study in Nature shows that the SARS-CoV-2 spike protein can inhibit DNA damage repair. It blocks the recruitment of critical proteins like BRCA1 and 53BP1 to repair sites. If our DNA can’t fix itself, mutations accumulate: the first step toward cancer.
3/ The P53 protein is known as the ”Guardian of the Genome” because it stops tumors. Research in the Journal of Infection shows that P53 is significantly downregulated during and long after infection. Losing this shield creates a high-risk environment for oncogenesis. 📉🦠
1/ Following the thread on the cumulative risk of Long COVID in children after reinfection, let's look at a new study on vaccination and adults. The evidence is overwhelmingly clear: vaccination is protective. #VaccinesWork #PublicHealth
2/ A massive Swedish nationwide study (Sahlgrenska Academy, European Heart Journal) of over 8 million adults confirms that full COVID-19 vaccination significantly reduces the risk of severe cardiovascular conditions linked to the infection.
3/ 📉 VACCINES REDUCE SEVERE RISKS:
After full vaccination (especially the 3rd dose), the risk of severe cardiovascular events—including heart attack, stroke, and heart failure—was generally 20-30% lower compared to the unvaccinated.
1/ 🚨 The Double-Edged Sword: New research suggests #SARSCoV2 might be an unseen accelerant for #LungCancer. Beyond acute illness, the virus's long-term effects could fuel cancer development and progression. This is a critical public health warning. 👇 #COVID19 #Oncology
2/ The study highlights several terrifying potential mechanisms:
Chronic Inflammation: The cytokine storm and persistent, dysregulated inflammation after COVID are well-known cancer promoters.
3/ ACE2 Receptor: SARS-CoV-2 binding disrupts the protective RAS pathway, potentially contributing to cancer progression.
Dormant Cells: Respiratory infections like COVID-19 can even wake up dormant cancer cells (DCCs) in the lungs, triggering metastasis.
1/ Marie Ewerz is 49. She got COVID in 2021 and has not been well since. Her symptoms are getting worse. 💔 Thousands in Sweden still suffer from a condition—Long COVID—that remains largely misunderstood, years after the first cases. Marie says: "You feel so alone."
@SwedishPM
2/ The illness has fundamentally changed her family life. At 9, her son first found her passed out on the kitchen floor. "He's been terrified and barely dared to leave me," Marie shares. Now 13, his worry meant he’s had to grow up too fast.
@Folkhalsomynd @jakobforssmed
1/ A new study on #LongCovid in children shows worrying results. Researchers found a strong link between persistent neuropsychiatric symptoms (like headaches, dizziness, and memory issues) and changes in brain volume, specifically in the temporal and subcortical regions.
2/ The study published in Pediatric Neurology found that children with more severe symptoms during the acute phase of COVID-19 were more likely to have significant brain volume changes months later. This suggests that the initial severity of symptoms can predict long-term effects
3/ Additionally, the research highlights that visual perception is also affected. Children with visual symptoms had lower scores on perceptual skills tests, pointing to potential underlying issues with how the brain processes visual information.