Conor Browne Profile picture
Aug 10 11 tweets 2 min read Read on X
1. I've said exactly this for quite some time. Expanding on Adrian's point here, Covid-19 has three distinct characteristics as a disease that enables it to be denied at a societal level.
2. First, none of its symptoms trigger the human disgust mechanism. Adrian gives a great example of this. The two key symptoms that distinguish Covid-19 from other common diseases are cognitive dysfunction and anosmia, both of which are *invisible* to other people.
3. In simulations I took part in long before the Covid-19 pandemic, diseases with symptoms that triggered the human disgust mechanism - symptoms such as disfigurement, vomiting, incontinence, bleeding, and convulsive syncope - were most likely to cause people to avoid infection.
4. Second, unlike other common diseases, Covid-19 is not generalisable. That is to say, unlike the common cold, influenza, or norovirus, one person's experience of the disease cannot be relied upon to accurately predict another's.
5. For example, if you're unfortunate enough to get norovirus, and then a month later a friend of yours gets it, you can describe to your friend exactly what his or her disease course is going to be like with a high degree of accuracy, based on your own experience.
6. Likewise with flu or the common cold. This is absolutely not the case with Covid-19. The wide spectrum of symptoms and severity of the disease means it is not easily generalisable in this regard. Just because 'it's the sniffles' to you does not mean it will be for your friend.
7. This inability to generalise the experience of Covid-19 sets it apart from other common diseases, and also, more profoundly, from our shared sociological understanding of how diseases operate in society. Fundamentally, one person's experience of the disease is not predictive.
8. This sets the scene for the disconnect we see across society today; because we are so used to being able to predict another's experience of a disease on the basis of our own experience of it, there is a constant, flawed, and ever-present societal assumption that Covid is mild.
9. Third, in my own experience, people do not understand Long Covid. They have a fixed view of it that can be summed up as 'severe symptoms that do not resolve'. It is also seen as rare, which is why I know people with Long Covid who don't know they have Long Covid.
10. In addition, the vast majority of people are not accustomed to viewing acute diseases as risk factors. Most people don't grasp that a cardiovascular event could be triggered by a mild bout of Covid-19 they had three months previously, for example.
11. These three factors: lack of triggering the human disgust mechanism, inability to be generalised, and lack of widespread understanding of sequelae of infection all contribute to the societal denial of the dangers of Covid-19.

/end

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More from @brownecfm

Aug 4
1. A recent conversation with a colleague threw into sharp relief exactly why I am so inspired to develop technologies to prevent pathogenic infection. So, if you'll indulge me, let me explain. In early 2002, I had what to all intents and purposes was a cold. Sniffles, cough etc.
2. I just took paracetamol and got on with it, and was completely fine in a few days. About a week later, I suddenly developed widespread and extensive muscle twitching - fasciculations. These fasciculations got severe really quickly, enough to cause chronic insomnia.
3. It's difficult to sleep with widespread muscle twitching, I assure you. These symptoms eventually led me to a neurologist, who diagnosed me with cramp-fasciculation syndrome (CFS). Later, another neurologist considered neuromyotonia to be a more accurate diagnosis.
Read 13 tweets
Jul 29
1. The most important concept in this excellent article is this:

'the team wanted to explore what he called a “*reciprocal relationship*” between COVID-19 and chronic conditions'.

* my emphasis
oregonlive.com/health/2025/07…
2. “If you had already had metabolic disease, like obesity, diabetes or hypertension, that meant that if you got COVID, it was going to be worse,” he explained. “On the other hand, there was a potential risk of new-onset metabolic disease after COVID.”
3. This reciprocal relationship is why unmitigated SARS-CoV-2 transmission will inexorably lead to decreasing population health, especially when you also consider that a new-onset metabolic disease *caused* by SARS-CoV-2 infection could be made *worse* by subsequent re-infection.
Read 4 tweets
Jul 14
1. Allow me to clarify, beginning with a definition: by 'rigorous indoor masking' I mean 'wearing a mask in all indoor public spaces'. This, of course, means no eating, although hydration is possible using a sip valve.
2. Why do I write that it can be really difficult? Because acknowledging the sacrifices that people have made as a result of rigorous masking - some for over five years now - to protect both themselves and others is very important.
3. Recognising hardship that people have embraced and continue to embrace for the good of themselves and others lets those people know that their hardship is both seen and appreciated. It is a validation of their efforts. Any leader will tell you how vital this is.
Read 10 tweets
Jul 13
1. Outstanding summary of a recently published study on cognitive dysfunction in Long Covid (link to study at end of thread). The important point here is the 20% prevalence of anosognosia: having cognitive dysfunction but not being aware of it.
2. This was also a finding of the SARS-CoV-2 Human Challenge Study.

From the Discussion: 'This apparent discrepancy between objective and subjective measures could be interpreted as indicating that the tasks are sensitive enough to detect small...
share.google/sh8p64mCjstfgX…
3... changes in cognition that are *too subtle for the volunteer to be metacognitively aware of*'

*my emphasis.

A growing percentage of the global population with cognitive dysfunction that they are not aware of will insidiously change human society.
Read 4 tweets
Jun 27
1. The prevailing discourse surrounding mitigating against SARS-CoV-2 infection is rife with false dichotomies. At a societal level, the most obvious of these is the notion that mitigation measures stand in opposition to economic growth, when, in fact, the opposite is true:
2. Mitigation measures - specifically widespread air filtration or purification - would increase economic growth, by virtue of reducing ill health in the workforce (implementing widespread passive mitigations would also increase operational resilience to future pandemics).
3. Likewise, at a personal level, the prevailing false dichotomy is that mitigating against infection is incompatible with human flourishing. This is also not the case, on two levels:
Read 8 tweets
Jun 23
1. There have been some exceptional comments on this thread, and as a result I'm going to recount a personal experience from 2020 that explains why I come down much harder on the side of incompetence rather than conspiracy.
2. When the UK 'Eat Out to Help Out' scheme was launched in 2020, I told every single person I knew not to take advantage of it. It's important to remember two points here: that this was before the availability of vaccines and that everyone I told knew and trusted my expertise.
3. Only two people I knew didn't take advantage of the scheme (and one of those people still hasn't had Covid). Everyone else basically said something along the lines of, 'I know you're right, but I'm willing to take the risk to have a good night out'.
Read 7 tweets

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