Thread by @kevinweil

💥 I’m starting something new inside OpenAI! It’s called OpenAI for Science, and the goal is to build the next great scientific instrument: an AI-powered platform that accelerates scientific discovery.

We’ll look to hire a small team of academics that are (i) world-class in their field; (ii) completely AI-pilled; and (iii) great science communicators. Paired with a small team of researchers, we want to prove that AI models are ready to accelerate fundamental science—and accelerate research all over the world.

Scientific discovery improves everything from the quality of our daily lives to national security to global GDP. Innovation is the reason the US leads the world. Few domains hold as much promise for improving lives as science.

GPT-5 is clearly a new threshold; below are four recent examples. There are many more, not to mention things like AlphaFold from our friends at GDM.

1. GPT-5 Pro was able to improve a bound in one of @SebastienBubeck's papers on convex optimization—by 50%, with 17 minutes of thinking.

https://x.com/SebastienBubeck/status/1958198661139009862

2. GPT-5 outlining proofs and suggesting related extensions, from a recent hep-th paper on quantum field theory [] arxiv.org/pdf/2508.21276…

3. Our recent work with @RetroBio_ , where a custom model designed much-improved variants of Nobel-prize winning proteins related to stem cells.

https://x.com/polynoamial/status/1958920311161925899

4. @DeryaTR_ has been a non-stop source of examples of AI accelerating his biological research, such as

https://x.com/DeryaTR_/status/1956871713125224736

I went to grad school to become a researcher in high energy physics, only to get nerdsniped into startups like so many others. I feel super fortunate now to get to combine both.

I’ll simultaneously begin working with @SebastienBubeck and the synthetic data team at OpenAI as an AI researcher to learn the craft. I’m grateful to him and his team for being willing to mentor me, and I’m eager to prove worth their time and effort!

I’m able to do this because the product and design leaders at OpenAI are amazing, and now are complemented by @fidjissimo beginning her role as CEO of Applications. OpenAI’s products have been my life since I joined, and they’re in great hands.

We’ll share more about OpenAI for Science in the coming months. In the meantime, if you’re an AI or academic researcher interested in joining us, my DMs are open.