Mr. Jack Profile picture
Sep 10, 2025 23 tweets 7 min read Read on X
This is Dr. Patrick Soon-Shiong.

He’s a surgeon who’s dedicated 50+ years to researching cancer.

His message? Cancer isn’t bad genes or random mutations—it’s your immune system failing.

This changes everything you’ve been told about how to fight & prevent cancer: 🧵 Image
Image
1/ Cancer rates are rising alarmingly

• Soon-Shiong sees 13-year-olds with pancreatic cancer
• Colleagues report 8-11-year-olds with colon cancer
• Young adults with aggressive cancers
• Cases showing "turbo-charged" progression

But why is that?
2/ For decades, oncology has operated on the premise:

"Cancer is fundamentally a genetic disease."

Despite billions spent on genetic research, survival rates for aggressive cancers like pancreatic cancer remain low.

Something crucial is missing in our understanding.
3/ Soon-Shiong's research points to an overlooked truth:

The mutations we observe are consequences, not primary causes.

The deeper issue? A compromised immune system failing to perform its function to eliminate abnormal cells.

But that's just the beginning...
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4/ Our bodies constantly produce potentially cancerous cells through normal division errors.

Evolution's solution: natural killer (NK) cells and T-cells that identify and eliminate these threats.

Soon-Shiong describes these as our "internal first responders."
5/ These immune cells represent an ancient defense system, perfected over millions of evolutionary years.

Remarkably, science only discovered NK cells in the 1970s, highlighting how recently we've begun to understand our own protection mechanisms.

The implications? Staggering.
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6/ Our immune system maintains an exquisite balance:

1. Defensive "killer" cells that eliminate threats
2. Regulatory "suppressor" cells that prevent autoimmune reactions

Cancer emerges when this balance tilts toward suppression.

But why does this happen in the first place?
7/ According to Soon-Shiong, cancer develops through two primary mechanisms:

• Cancer cells "hide" from killer cells
• Cancer cells activate suppressor cells, shutting down your natural defense system

This allows rapid, unchecked growth.
8/ This explains why people with identical cancer mutations have drastically different outcomes.

The difference? Immune function and metabolic health.

What does this tell us about prevention?
9/ Research reveals a critical overlooked marker:

Absolute Lymphocyte Count (ALC).

Studies show low lymphocyte counts predict poor outcomes across all cancer types—yet most oncologists don't prioritize this measurement.
10/ Standard cancer treatments often undermine immune function:

• Chemotherapy severely depletes lymphocytes
• Radiation damages NK cell populations
• Steroids suppress critical immune responses
• Chronic inflammation converts killer cells to suppressors

This creates a paradox...
11/ Treatments initially shrink tumors while destroying the very immune cells needed for lasting remission.

"Winning the immediate battle but losing the long-term war," as Soon-Shiong describes it.
12/ What damages our immune system in the first place?

• Chronic inflammation (key driver)
• Toxins in processed foods
• Environmental pollutants
• Viral infections
• Chronic stress
• Poor sleep disrupting NK cell replenishment
13/ Soon-Shiong's research on cancer triggers revealed a common pattern:

Nearly all disrupt the balance between killer and suppressor immune cells.

Revolutionary implication: diverse cancer causes share one fundamental mechanism.
14/ Soon-Shiong made a surprising discovery when studying tumor genetics.

Cancers we name by location (lung, breast, pancreas) often have identical molecular signatures.

This means a drug for 'breast cancer' might work on colon cancer.
15/ Soon-Shiong's research reveals we must look beyond genetics to protein pathways.

"The gene doesn't dictate treatment—the activated protein does."

Most cancer genomics programs miss this crucial distinction, leading to suboptimal treatment selections.
16/ Based on his research, Soon-Shiong recommends evidence-based protective strategies:

• Prioritize quality sleep (essential for NK cell regeneration)
• Regular sun exposure (specific wavelengths activate immune cells)
• Minimize inflammatory foods and chemicals

But there's one factor above all others...
17/ Additional research-supported immune-enhancing approaches:

• Time-restricted eating patterns
• Strategic exercise approaches
• Stress reduction techniques
• Optimizing metabolic markers
• Minimizing exposure to immunosuppressive toxins

What ties these all together?
18/ "Cancer doesn't develop in a body with healthy mitochondria and functioning immunity."

His decades of research suggest cancer prevention begins with protecting these fundamental biological systems.

The question is: Are you ready to implement this knowledge?
19/ DISCLAIMER: This is NOT medical advice.

Cancer is highly complex and no single theory can fully explain its development and progression.

It's for educational purposes only.
I hope you've found this thread helpful.

Follow me @MrJack6590 for more.

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