From a study of 97 participants who had tested positive for SARS-CoV-2 before the vaccines were widely available (until September 2021) in Cape Town,
"The results were striking:
- More than half had at least one ongoing symptom more than six months after infection.
- 44% showed measurable cognitive or memory impairment, while 53% reported memory problems.
- 55% reported moderate to severe fatigue.
- One in four had high anxiety levels, and the number taking psychiatric medication nearly doubled after infection.
- Severity didn’t predict outcome: These problems affected people across all levels of illness, including those who were never hospitalised.
- None of the inflammatory, cardiovascular, or renin–angiotensin markers measured during acute illness or recovery were linked to persistent symptoms. In short, the usual blood tests taken during infection didn’t help identify who would go on to develop long COVID symptoms..
All these reported symptoms were new to the individuals and only came after COVID..
The lack of a clear biological predictor suggests that long COVID’s mental and cognitive effects aren’t easily explained by inflammation alone.."
SARS-CoV-2 can directly damage our nervous system.
'Long COVID’s hidden toll: the South Africans still battling fatigue, anxiety and memory loss' gavi.org/vaccineswork/l…
• • •
Missing some Tweet in this thread? You can try to
force a refresh
@PaulRoundy1 No, Paul. I see that the neurologic complications in children is becoming more prevalent since last year (i.e., after the appearance of the Omicron strain).
@PaulRoundy1 FYI, in Japan, among the officially reported COVID deaths of children from Jan. to Sep., 2022, the major endogenous cause was central nervous system symptoms (19/50; 38%), which is much higher than circulatory (18%) & respiratory (8%) ones.
@PaulRoundy1 I should note that, as a feature of deaths due to the central nervous system abnormalities, the durations from onset to death of those children were quite short: 3.0 days in median with 0-2 days: 46%, 3-6 days: 29% & 7 days or more: 25%).
Let me note below the failures that we experienced in international cooperation for controlling the COVID-19 pandemic: 1) the lack of timely notification of the initial outbreak of COVID-19;
...
(1/6)
2) costly delays in acknowledging the crucial airborne exposure pathway of the virus, and in implementing measures; 3) the lack of coordination among countries regarding suppression strategies;
(2/6)
4) the failure of governments to examine evidence and adopt best practices for controlling the pandemic; 5) the shortfall of global funding for low-income and middle-income countries (LMICs);
(3/6)
1/11
The National Institute of Infectious Diseases (NIID), the authority on infectious disease issues in Japan, published a report on 30 June 2022 entitled "Acute hepatitis of unknown etiology in children in Japan (1st report)".
2/11
The report revealed details of pathogen testings regarding the children's acute hepatitis for different age groups based on of a survey performed by the Ministry of Health, Labor and Welfare of Japan (& NIID) for the period from 1 October 2021 to 23 June 2022.
3/11
Among 62 children (male: 34, female: 28, median age: 5 yo) with the acute hepatitis of unknown etiology,
- 57 of 61 cases (93%) were detected in the week of 14 February 2022 or later.
- 12 of 55 cases (22%) were at least once vaccinated;
2/3 The 62 cases met the following criteria:
-Period: From October 1, 2021 to June 23, 2022;
-Patient: Hospitalized children of 16 y/o or younger;
-Symptoms: Acute hepatitis with AST or ALT exceeding 500 IU/L without involvement of hepatitis A to E viruses.
3/3 Among the 62 cases,
- adenovirus positive: 5 cases (type 1 & 2: 2 cases and type unknown: 3 cases);
- SARS-CoV-2 positive:5 cases;
- these PCR tests were performed when their symptoms were recognized;
- liver transplant: 0;
- 7 cases are still under complete checkup.