The key finding:
👉 Strong recommendations AGAINST injections
WHY?
Because benefits are:
• Small
• Often clinically trivial
• Short-lived
Other issues include
• Cost
• Burden
• Procedural risks (infection, dural puncture, neuro complications etc )
Even if rare—they matter at scale.
I understand this research and why the recommendations were made but cant fully endorse the findings for 3️⃣main reasons....
1️⃣ Because many patients (in my experience) still get meaningful benefit from injections post >3 months after onset of pain.
This pain reduction (although temporary) can be a very helpful to provide a window to perform rehab, improve patients physical condition and help them to move towards self-efficacy.
2️⃣ By the time many patients seek care and are then referred to pain services it is normally > 3 months.
In our service from the time of referral to the pain team is >1 year.
Should we exclude these patients from pain care altogether?
3️⃣ Radicular symptoms can easily last 6-12 months after onset. Should we deny people extra pain relief over this time if conservative measures and oral analgesia are implemented but minimally effective (and surgery is not a strong option)?
🙋♂️Ask any sciatica patient if they would like 8-12 weeks of reduced pain.....the answer would be unanimous I reckon....
Final Thoughts 💭
• There are undoubtedly patients who are having repeated, ineffectual injections out there and we definitely want to see less of this.
• But should this come at the expense of denying relief to a certain number of patients who actually need it?
• In a condition like radiculopathy which can be very recalcitrant and where treatment options are not plentiful, taking one therapeutic agent off the table so soon (>3months) seems too stringent in my book.
👉Making blanket rejections seem heavy-handed to me.
👉 I favor a balanced approach guided by individual patient needs - not hard time cutoffs.
Lumbar Radicular Pain ('Sciatica') is pain that originates from irritation or compression of the lumbosacral nerve roots.
Although text books would state that pain will lie in a dermatomal pattern -
The reality is that pain is non-dermatomal in >60% of cases (Murphy et al 2009)
Most patients will have pain that cross multiple dermatomes.
Images below come from Hasvik (2022) where they diagnosed disc herniations + nerve root compression based on clinical exam and imaging.
The 4️⃣ Regions of Lumbar Disc Herniation and why Location Matters.
A 🧵.....
The location of the disc herniation is extremely important as it is related to the nerve root or roots that can be compressed
The 4 main locations are: 1. Central 2. Subarticular ("Paracentral/Paramedian") 3. Foraminal ("Lateral recess") 4. Extraforaminal ("Far Lateral")
Lets go through each
1️⃣ Central disc herniations are usually the most serious.
Hernations here will impact the central canal and therefore are highly implicated in the development of Cauda Equina syndrome.
They can also potentially rupture the posterior longitudinal ligament
Based on our recent double publication on trunk strength and endurance testing I wanted to give a synopsis of the most common and most studied trunk endurance test- The Biering-Sørensen Test (BST).
WHAT IS IT?
The BST assesses isometric endurance of the trunk extensors and posterior chaing.
It was developed by Fin Biering-Sørensen, a Danish doctor, in 1984.
It his seminal study he found that men with holding times of <176 seconds had a greater chance of developing LBP in the coming 12 months.
He promoted > 3 min holding times to prevent LBP
Since then it has been studied extensively and has been shown to be both reliable and valid in those with and without back pain.
Foraminal stenosis is defined as an entrapment-type radicular presentation due to stenosis of the nerve root canal in the intervertebral foramen
It can be determined on MRI as per image below.
Note the nerve root between the white arrow.
See the nerve roots above and below - the white ring around the black dot denotes perineural fat.
In general the less white (fat), the greater the stenosis and degree of nerve root compression
There are multiple causes
Advanced Disc Degeneneration (Height loss)
The height of the motion segment notably decreases due to disc degeneration and dehydration.
There are 3 physiological processes thought to be involved in "Exercise-Induced-Analgesia"
1️⃣ Endocannabinoid and Opioid Mechanisms
2️⃣ Release of anti-inflammatory cytokines
3️⃣ Reduced Stress-induced hyperalgesia
1️⃣ Endocannabinoid and Opioid Mechanisms
Cannabinoid and opioid release can occur post exertion in exercise. These are potent analgesics.
This has been shown in aerobic exercise but has also been shown using an isometric handgrip exercise for three minutes at only 25% MVC.