Georgios Pappas Profile picture
May 5 6 tweets 2 min read Read on X
Hantavirus in a cruise ship, looks like Andes virus, looks like a voyage of the damned:
1. Trip starts in Argentina, where South American Hanta, Andes virus, is endemic. Patient No 1 rapidly deteriorates, meaning that he was infected before boarding (incubation 20 days) . Image
2. The following cases developed symptoms about 20 days later, a period consistent with being infected from patient No1. Andes is known as the only Hanta to transmit from person to person, studies from both Argentina and Chile have shown it is plausible.
nejm.org/doi/full/10.10…
3. Symptoms, as described by WHO, included respiratory failure but also initially diarrheas, all consistent with Andes descriptions. who.int/emergencies/di…
4. We can't be sure how this will evolve aboard the ship: you need, given the protracted incubation period, 40 days from last contact with an infected, to feel safe transmission has ended. Also trace the ones that flew with the ailing patient 2
5. No treatment, no vaccine. Limited awareness. In Greece there was needless talk today, despite normally having annual cases- we had a significant outbreak in Ioannina some decades ago, and we had described isolated cases too in the following years.
sciencedirect.com/science/articl…
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More from @GeorgiosPappas6

Apr 13
Nature remains a massive biological laboratory- Humans increasingly tend to intrude and interact with unknown ecosystems, aggravating the risk of novel zoonotic spillovers. I have written about how we can avert future outbreaks in @BulletinAtomic 1/n thebulletin.org/2026/04/python…
Python Cave, Uganda, home to bats that transmit Marburg (twice in the past), is still a tourist site. Access was restricted and an observatory was built, but surveillance videos showed tourists and schoolchildren, nearing unprotected the cave entrance 2/n biorxiv.org/content/10.110…
Even worse, a variety of animals were recorded scavenging the cave bats, the majority of them potential bushmeat. A typical example of a killer pathogen able to escape its cave and cause outbreaks, either directly or through an intermediate animal. 3/n
Read 9 tweets
Mar 21
"Our greatest test will be our testimony"
Το να πρέπει να υπερασπιζόμαστε τα στοιχειώδη (στην δημόσια υγεία) είναι τραγικό. Ο αντιεμβολιαστικός λόγος, αν αθροίσουμε τα ποσοστά των κομμάτων που τον εκφράζουν, είναι αξιωματική αντιπολίτευση. open.spotify.com/episode/5XEZi2…
Αν είχαν κλείσει τα σύνορα της Κίνας τις αρχές του 2020. Αν είχαμε δίκτυα άμεσης αντιμετώπισης στην κοινότητα, επίθεσης στον ιό. Αν δεν περνούσαμε συλλογικά εκείνο το καλοκαίρι της αφασίας του 2020, νομίζοντας πως ξεμπερδέψαμε και χωρίς καμία προετοιμασία tinyurl.com/38d8nf77
Read 13 tweets
Aug 26, 2024
I am writing in the @BulletinAtomic about the new mpox variant that is taking off in Africa and caused WHO to declare a public health emergency of international concern. But the WHO plan for stopping it isn’t realistic, and major issues are ignored 1/n thebulletin.org/2024/08/a-new-…
There is a new variant, Clade Ib, of the traditionally considered more morbid Clade I (the mpox Western World epidemic was Clade II). Concern was raised as its description referred to extensive human to human transmission, implicating sex workers too 2/n nature.com/articles/s4159…
But the Africa CDC epidemiologic reports are clear: in the rapidly escalating, and due to confirmed Clade Ib, outbreak, it's children that comprise the majority of cases. It may travel through adult networks but then goes home? 3/n africacdc.org/download/afric…
Read 12 tweets
Jul 30, 2024
Δέκα σημεία για τον κορωνοϊό: (ευχαριστώ ειδικά την Ιωάννα Σουφλέρη για το βήμα στο Βήμα) , καθώς ο αριθμός των κρουσμάτων, ειδικά το τελευταίο 48ωρο, είναι επιεικώς δυσοίωνος- 1/n tovima.gr/print/opinions…
Δεν είναι νέα τα σημεία: απλά ο ιός συνεχίζει να σκοτώνει δεκάδες εβδομαδιαίως, με αυξητική τάση (35 οι νεκροί την προπροηγούμενη εβδομάδα κατά ΕΟΔΥ), επιβαρύνει την γενικότερη μεσοπρόθεσμη νοσηρότητα, καταλείπει long covid, 2/n
ενώ συνεχίζουμε να σνομπάρουμε την μάσκα, να αγνοούμε την σημασία του καθαρού αέρα εσωτερικών χώρων, να επιτρέπουμε την ενδονοσοκομειακή μετάδοσή του, να μην επενδύουμε στην επιστημονική εγγραμματοσύνη. 3/n
Read 4 tweets
May 3, 2024
Writing in @BulletinAtomic on the current H5N1 (and cattle and milk) situation, plus some May 3 updates, or how avian flu keeps getting closer to humans- but how close? is it pandemic close? (obliged to @MatthewField2) 1/n
thebulletin.org/2024/04/bird-f…
An important new preprint outlines that this was a single avian-cattle spillover event, and subsequent interstate cattle movements facilitated transmission between herds and some initial further mammal adaptations 2/n biorxiv.org/content/10.110…
A pathology study recently published by @EIDjournal confirms that cattle, contrary to cats, do not experience fatal disease- H5N1 has a predilection for mammary glands and their product, milk 3/n wwwnc.cdc.gov/eid/article/30…
Read 8 tweets
Apr 26, 2024
Γιατί αναζωπυρώθηκε η ανησυχία για την γρίπη των πτηνών, τι σημαίνει ότι προσβάλλει αγελάδες, είναι ασφαλές το γάλα, θα κάνει πανδημία ο H5N1; Στο @BulletinAtomic συνοψίζω την τρέχουσα κατάσταση και το αν είναι εύλογες οι ανησυχίες 1/n thebulletin.org/2024/04/bird-f…
Βασικές υπενθυμίσεις1 : η γρίπη των πτηνών, που δεν μεταδίδεται από άνθρωπο σε άνθρωπο, αλλά και για την οποία δεν έχουμε ως είδος κάποια ιστορική ανοσία, τα τελευταία 2-3 χρόνια έχει κάνει τεράστια εξελικτικά άλματα, προκαλώντας μαζικούς θανάτους διαφόρων ειδών πτηνών... 2/n
Βασικές υπενθυμίσεις2: εγκαταστάθηκε και στην Αμερική, αναπτύσσοντας προσαρμογή και μολυσματικότητα για θηλαστικά, με αποτέλεσμα μαζικούς θανάτους ειδών (π.χ. θαλάσσιοι λέοντες στη Νότιο Αμερική). Η προσαρμογή στα θηλαστικά εγείρει ανησυχία προσαρμογής και στον άνθρωπο. 3/n
Read 15 tweets

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