your ribosome is not a machine. it’s a computer. and we just found DHX29, which i’d call part of its operating system. thread 🧵
your DNA is an instruction manual written in three-letter words called codons. each word tells the cell which amino acid to add when building a protein
but the ribosome — the thing that actually builds the protein — can’t read DNA directly. it reads a copy called mRNA. and it doesn’t go fetch the amino acids itself
As someone who actively works in drug discovery, I want to dispel a myth.
Stimulants were not “designed for ADHD.” They were discovered by accident in the 1930s because they calmed hyperactive boys.
Also the origin story of the most prescribed psychiatric drugs in history.
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The entire research pipeline - the clinical trials, the diagnostic criteria, the dosing models - was built around one phenotype: hyperactive boys who couldn’t sit still in class.
Most stimulant studies were conducted on white males. The DSM criteria? Based on young boys.
I have ADHD. I’ve had it diagnosed since I was very young. And my meds genuinely helped me. I’m not anti-medication. Stimulants changed my life in real ways. But they fixed my hyperactivity. They did NOT fix my inattentiveness.
I just asked myself the most important question I’ve ever asked.
What if, god forbid, I had cancer right now? How would I save my life and would I be able to do it without Precigenetics?
The answer made me cry.
Here’s EXACTLY how I would save my own life TODAY. 🧵
Let me show you both paths. What happens today, without this platform
and what I’d actually do if I had one. Assume I had the permits to use my cells, and I could do what I want.
Then you tell me which world you want to live in.
the current reality for every cancer patient on earth:
You get a biopsy. Your tissue is fixed, stained, and sent to a pathology lab. It’s dead. The cells you need answers from are killed in the process of examining them.
how do we know that people in the past had cancer and when did we even know what cancer was?
a word for cancer existed long before microscopes or pathology.
the history of cancer is far more exciting than we realize.
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the idea is older than modern medicine. Hippocrates (400 BCE) used the word karkinos (crab) for tumors with “claw-like” spread. Galen (200 CE) expanded it. the word cancer is a translation of this lineage.
this existed across civilizations
in India, texts like Sushruta Samhita circa 600 BCE described “arbuda”: hard, immobile, enlarging masses that ulcerated and killed slowly. not called “cancer,” but the descriptions line up with malignancies.