1/ The answer to our last poll: cisplatin

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Below, a brief #tweetorial to walk through a simplified approach to #hyponatremia

Step 1: What type of hypoNa are we dealing with here?

Ex: Na 128 meq/L, glucose 500 mg/dL, BUN 20 mg/dL serum osm 292 mosm/kg 2/

Remember the difference between tonicity (a measure of EFFECTIVE osmoles) & osmolality (measure of both EFFECTiVE & INEFFECTIVE osmoles)

Effective osmoles cannot cross between the ECF and ICF, thus draw water across the cell membrane.

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1/

In this #tweetorial, we'll walk through our approach to uncovering #acidbase disorders & our mnemonic #pLACO using this example:

pH 7.28, pCO2 30, pO2 75
Na 145, Cl 103, HCO3 18
Albumin 4 mg/dL

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Step 1: what does the "p" in pLACO stand for? 2/

#pLACO

The p is for pH, which tells us how acidic/basic a solution is.

Normal arterial blood pH is 7.4. Anything less than that is acidEMIC and anything greater is alkalEMIC.

In our example, the pH is 7.28. Thus, we have an acidemia.

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