Discover and read the best of Twitter Threads about #2⃣
Most recents (5)
🧵Stitching together the truth. One thread at a time. 🚨On the Board of Directors for the company that makes #Moderna's #COVID19 vaccine are many names I've looked into. One name I hadn't yet investigated is one of MOST important: Mitch Daniels Jr.🔍 
1/8🧵If you're from Indiana, you probably already know Mitch Daniels. Listed as a founding director for Resilience, he's best known for being the 49th Governor of Indiana but tbh that's the least important detail of Daniels.
2/8🧵 His position as director for Moderna's manufacturing company couldn't be more sinister. Here's 5⃣ main reasons why: 1.) He started the first 13yrs of his career working for Senator Richard Lugar, of bio-lab/Lugar Center in Tbilisi, Georgia.
#JaiHind @samarkohli ji,
I see all Indians as one. I have no interest in comparing one state to another. It make no difference to me. However such falsehoods need to be debunked with facts & fuigures. So hear you go, lets demolish these false claims, one by one 🧵👇
1/n
I see all Indians as one. I have no interest in comparing one state to another. It make no difference to me. However such falsehoods need to be debunked with facts & fuigures. So hear you go, lets demolish these false claims, one by one 🧵👇
1/n
Claim #1⃣ - Punjab feeds the nation:
In wheat production Punjab is at #3, preceded by MP-#2 & Up=#1
2/n
In wheat production Punjab is at #3, preceded by MP-#2 & Up=#1
2/n
In rice production, Bengal is #1, followed by UP-#2, and then Punjab at #3.
There is no way that "Punjab is feeding the nation", That claim should go to UP, MP & Bengal.
3/n
tractorjunction.com/blog/top-10-ri…
There is no way that "Punjab is feeding the nation", That claim should go to UP, MP & Bengal.
3/n
tractorjunction.com/blog/top-10-ri…
@TumorBoardTues @ASCO @JohnEbbenMDPhD @SushmaJonna @HeekeMd #TumorBoardTuesday
#ASCO22 Biomarker Recap
😀Don't know about you all - but I had a great time at the meeting this year!
👉I will🔦a few biomarker based studies that caught my👁️
😉Did you notice that TWO of the plenary abstracts were for biomarker based trials‼️
#ASCO22 Biomarker Recap
😀Don't know about you all - but I had a great time at the meeting this year!
👉I will🔦a few biomarker based studies that caught my👁️
😉Did you notice that TWO of the plenary abstracts were for biomarker based trials‼️
@TumorBoardTues @ASCO @JohnEbbenMDPhD @SushmaJonna @HeekeMd @pashtoonkasi @KReissMD @DrR_DUNNE @FogacciJoao @AJacomeMD @OncBrothers @oncologician @DrSteveMartin @stolaney1 #TumorBoardTuesday
#1⃣
✅Dr. Yoshino🧑🏫the results of the Ph 3 PARADIGM trial
➡️FOLFOX-Pani vs. FOLFOX-Bev for RAS WT left CRC
👉823 Pts
👏OS>with Pani 36.2 vs. 31.3 months
👏ORR also > with Pani 75% vs. 67%
🤔BUT the curves don't separate until 26 months❓
🔎Abstract #LBA1
#1⃣
✅Dr. Yoshino🧑🏫the results of the Ph 3 PARADIGM trial
➡️FOLFOX-Pani vs. FOLFOX-Bev for RAS WT left CRC
👉823 Pts
👏OS>with Pani 36.2 vs. 31.3 months
👏ORR also > with Pani 75% vs. 67%
🤔BUT the curves don't separate until 26 months❓
🔎Abstract #LBA1
@TumorBoardTues @ASCO @JohnEbbenMDPhD @SushmaJonna @HeekeMd @pashtoonkasi @KReissMD @DrR_DUNNE @FogacciJoao @AJacomeMD @OncBrothers @oncologician @DrSteveMartin @stolaney1 #TumorBoardTuesday
#2⃣
✅Dr. Modi🧑🏫the results of the Ph 3 DESTINY-Breast04 trial
➡️T-DXd vs. SOC for HER-2 low metBreast Ca
👉557 Pts
👏PFS>with T-DXd 10.1 vs. 5.4 months
👏OS also > with T-DXd 23.9 vs. 17.5 months
🔎Abstract #LBA3
#2⃣
✅Dr. Modi🧑🏫the results of the Ph 3 DESTINY-Breast04 trial
➡️T-DXd vs. SOC for HER-2 low metBreast Ca
👉557 Pts
👏PFS>with T-DXd 10.1 vs. 5.4 months
👏OS also > with T-DXd 23.9 vs. 17.5 months
🔎Abstract #LBA3
🚨Acute #stroke case (from the archive):
Patient in 60s presents with sudden onset fluctuating LOC, dysarthria, mild right arm weakness (disabling)
Last seen normal 2hrs (witnessed onset).
You urgently take to CT- motion artifact, no clear early ischemic changes. CTA normal.
Patient in 60s presents with sudden onset fluctuating LOC, dysarthria, mild right arm weakness (disabling)
Last seen normal 2hrs (witnessed onset).
You urgently take to CT- motion artifact, no clear early ischemic changes. CTA normal.
2 schools of thought/approaches:
Approach #1⃣: Acute onset, disabling symptoms- proceed with lytic 💉and defer CTP
Approach #2⃣: Dx is still a bit unclear (ddx: seizure⚡️, etc)- proceed to CTP
If in camp #2, here are the CTP maps (CBF, MTT, Tmax>8s)
Approach #1⃣: Acute onset, disabling symptoms- proceed with lytic 💉and defer CTP
Approach #2⃣: Dx is still a bit unclear (ddx: seizure⚡️, etc)- proceed to CTP
If in camp #2, here are the CTP maps (CBF, MTT, Tmax>8s)
CTP confirms suspected localization of left thalamus (with possible internal capsule involvement).
CTP helped confirm the etiology (not a mimic), but delayed lytic administration by about 7-10 min (did not change management).
Which camp/approach are you in for this case🧠?
CTP helped confirm the etiology (not a mimic), but delayed lytic administration by about 7-10 min (did not change management).
Which camp/approach are you in for this case🧠?
How often do you check for Primary Aldosteronism (PA)?
Chances are, NOT nearly often enough!
VA study reveals widespread undertesting...can we do better?
acpjournals.org/doi/10.7326/M2…
If you've seen 10 pt's with HTN ➡️ you've probably seen PA!
Let's review in this #medtweetorial
Chances are, NOT nearly often enough!
VA study reveals widespread undertesting...can we do better?
acpjournals.org/doi/10.7326/M2…
If you've seen 10 pt's with HTN ➡️ you've probably seen PA!
Let's review in this #medtweetorial
I feel comfortable diagnosing Primary Aldosteronism
3/ First, why even check for PA?
🚫🦓It's NOT a zebra‼️
It IS one of the most common causes of 2* HTN:
📛5-10% of those w/ HTN
📛20% w/ resistant HTN
Have you seen 10 patients with HTN?
If yes, you've likely seen PA!
🚫🦓It's NOT a zebra‼️
It IS one of the most common causes of 2* HTN:
📛5-10% of those w/ HTN
📛20% w/ resistant HTN
Have you seen 10 patients with HTN?
If yes, you've likely seen PA!
