Most recent unrolls from @ThreadReaderApp

Apr 18
Officer Lt. Matthew Mahl, a longtime member of the D.C. Metropolitan Police and former chairman of the police union was arrested in Maryland and charged with sexual solicitation of a minor and soliciting child sex abuse materials.
1)
He was elected around 2016 as the first openly gay chairman of the D.C. Police Union, according to multiple reports from his tenure as a lieutenant in the Metropolitan Police Department.
2)
This distinction was noted in coverage of his role supervising the Gay & Lesbian Liaison Unit in 2013 and his later leadership positions.

Investigators say he communicated with someone he believed to be a 15-year-old boy, who was actually an undercover detective.
3)
Read 6 tweets
Apr 18
Chromothripsis is typically triggered by errors during mitosis, such as the formation of a micronucleus. Recent research suggests that deuterium overload can play a role in this "shattering" process:

Kinetic Isotope Effect (KIE): Deuterium (D) forms bonds that are 8-10 times stronger and harder to break than normal hydrogen (H).

Mitotic Disruption: This mass difference can cause "stutters" in the molecular motors (like Fo-ATPase pumps) that manage energy and cell division. When these motors fail, chromosomes are more likely to lag behind or mis-segregate into micronuclei, leading directly to the shattering seen in chromothripsis. Kev is right chromothripsis is down stream deuterium biology because the KIE controls clock speeds and a slow clock causes cancer because atomic mass (D+) is weighing down the DNA and it cannot be read on time.

The base chain of life, DNA is designed to be undeuterated to get perfect signal and eliminate the noise cause by deuteration.
2. What does this slide really mean? The slide highlights a massive biophysical paradox that mainstream medicine largely ignores: Deuterium is the most concentrated "vital element" in human serum, yet it is functionally excluded from the mitochondria. Rockefeller medicine teaches MDs to focus on glucose and K+ but deuterium has 10X the concentration in blood where no RBC have mitochondria because of this partitioning.

When a cell has mitochondria, our human Langrangian seeks to keep it from the matrix at all costs. When it gets this is when cancer becomes a real possibility.

H+ breaks time symmetry in mammals so we can live in a highly dissipative state, while D+ invites symmetry and this leads to disease and eventual rigor mortis. Life is not meant to be symmetric or at equilibrium. That is why biochemists are morons and why biophysics shows the equation of Everything. H+ and D+ are handled asymmetrically in the eukaryotic kingdom.Image
Image
3. Methylation and "Heavy" DNA:

As my thesis notes, methyl groups (𝐶𝐻3) are central to DNA regulation. When these groups are deuterated (CD3)

Gene Expression: Research indicates that a higher D/H ratio in the cell acts as a "trigger" for oncogenes like c-Myc and RAS while suppressing tumor suppressors like TP53.

Methylation Patterns: Altered D/H ratios can disrupt the tight regulation of DNA methyltransferases, potentially leading to the global hypomethylation and site-specific hypermethylation that characterize cancer. They also alter the UPE signal need to progress past mitosis ibn the cell cycle.
Read 5 tweets
Apr 17
Sneako inexplicably being indulged by world leaders like the Prime Minister of Malaysia now - as well as major third world thinkers and personalities. Like it or not Sneako represents a unifying force in the Ummah, the Ummah love him. Sneako could become leader of a new Caliphate Image
This is the spectrum of Sneako-ist Thought
Sneako is the Zeitgest and the Zeitgeist is Sneako
Read 4 tweets
Apr 17
If you’re not using Claude at work, you’re already behind.

Here are 10 copy-paste prompts to save hours every week and do better work: Image
1. Turn messy notes into a polished update

“Convert the notes below into a clear work update for [manager/team/client].

Goal: explain what was done, what matters, blockers, and next steps.

Tone: professional, direct, confident.

Format:

· Summary
· Progress made
· Risks/blockers
· Next actions

Keep it under [150 words]. Remove repetition and make weak points sound crisp but honest.

Notes: [paste notes]”
2. Write better emails fast

“Write an email to [person/role] about [topic].

My goal is to [inform / request / persuade / follow up].

Context: [paste context].

Tone: [warm / professional / firm / concise].

Constraints: [max length / deadline / specific ask].

Return 3 versions:

1. Very concise
2. Friendly and polished
3. More persuasive

Also give me 5 subject line options.”
Read 11 tweets
Apr 17
OMG

Kash Patel a drunken national security threat

"Meetings and briefings had to be rescheduled for later in the day as a result of his alcohol-fueled nights."

"A request for 'breaching equipment'...was made last year because Patel had been unreachable behind locked doors." Image
2/ How long has the White House known this and let Patel keep his job?

How long has Todd Blanche known this?

theatlantic.com/politics/2026/…
3/ Seems to have been widely known.

Sourcing: "six current and former officials and others familiar"
Read 5 tweets
Apr 17
Hollywood is two decades ahead of the narrative and the scientific consensus. In the movie The Core (2003), the U.S. government hires a skilled computer hacker named Theodore Donald "Rat" Finch to assist in a critical mission to save Earth.

The planet's molten core has mysteriously stopped rotating, causing the electromagnetic field to deteriorate, which threatens catastrophic global consequences. Rat, widely regarded as one of the best hackers in the world, is recruited specifically to control the flow of information on the internet and prevent public panic by keeping news of the impending disaster under wraps.

His role involves scouring the web and suppressing leaks about the crisis and the government's secret plan to drill into the Earth's core and detonate nuclear explosions to restart its rotation. (1/9)🧵Image
In January 2023 a groundbreaking study by Yi Yang and Xiaodong Song proposed that Earth’s inner core had recently slowed down and may have started to rotate in the opposite direction.

The movie’s plot revolves around a weakening magnetic field and a slowing inner core—how on Earth did they predict this possibility twenty years before science caught up? (2/9)🧵Image
The hiering of 'rat' to supress information about the upcoming doomsday scneario is another thing they got it right.

Have you heard about PEADs?

The Presidential Emergency Action Documents (PEADs) were created during the Eisenhower Administration in the 1950s as part of continuity-of-government plans in case of a nuclear attack.

However, they actually address a wide range of apocalyptic scenarios, many of which are highly classified. (3/9)🧵Image
Read 9 tweets
Apr 17
You’ve probably heard this more times than you can count:

“I got the COVID vaccine and nothing bad ever happened to me.”

There’s a reason for that… not everyone got the same thing.

And a peer-reviewed study backs it up.

In 2023, Max Schmeling and colleagues discovered that just 4.2 percent of the COVID vaccine batches accounted for 71 PERCENT of suspected adverse events.

Additionally, about two-thirds of the batches had a low to moderate risk of adverse events.

And about one-third had little to no risk of adverse events. “Nothing happened.”

The chart below shows how extreme this variation actually was.

“The shot [batch] was deterministic for who was going to have a serious event or not.” That’s the conclusion from renowned cardiologist Dr. Peter McCullough.

If “hot lots” showed up in the COVID shots, that raises a bigger question about other vaccines.

What if this wasn’t a one-time issue? Let’s take a look. 🧵
For over a century, one assumption has quietly shaped public trust:

If a vaccine is approved, what’s in each vial must be safe and consistent.

Same dose. Same safety. Same outcome.

But history tells a very different story.

Because again and again, the real danger wasn’t always the vaccine itself… Sometimes it was the batch.Image
There’s a term most people have never heard: “Hot lots.”

It refers to vaccine batches that are unusually toxic, contaminated, improperly processed, or far more likely to cause severe reactions than other lots.

And once you start looking, they don’t appear once. They appear everywhere.Image
Read 32 tweets
Apr 17
@ClaudioBorghi @PatriotsEU Caro Claudio,tu e Alberto siete l'unico motivo per cui voto ancora.Avete avuto la costanza di spiegare cose che mai avrei pensato di poter capire,ma ci siete riusciti con tanta pazienza...Vi seguo dal gennaio 2012 quando, per caso, sono capitato sul blog di @AlbertoBagnai 1/
@ClaudioBorghi @PatriotsEU @AlbertoBagnai Tante cose sono successe da allora ma purtroppo alcune sono rimaste invariate;gli allocchi vanno sempre dietro agli specchietti (prima si chiamavano Meloni, adesso Vannacci) ma nessuno si ricorda di chi,furante la pandemia,voleva far approvare il modello Novi a livello nazionale,
@ClaudioBorghi @PatriotsEU @AlbertoBagnai Cosa che avrebbe fatto decadere tutti gli obblighi tanto invisi ai vari leoni da tastiera. La Meloni, allora, ha fatto la figura dell'opposizione dura e pura restando fuori dai giochi, quando entrando anche lei al governo avrebbe dato molto più peso al centro-destra... se solo
Read 8 tweets
Apr 17
「日経平均株価」「S&P500」「オルカン」
トリプル最高値を更新

投資の神様ウォーレン・バフェットなら
こう言うだろう

「いま、やるべきことは1つだけ
絶対に相場を予想してはいけません」

「数多の暴落と急騰を見てきたが
勝ち残ったのは予測した人ではなく
規律を守った人」…↓(1/6)
なぜ今、最高値を更新し続けるのか
それは「株が高い」のではなく
「現金の価値が目減りしている」から

インフレにより物価が上がれば
企業の売上も利益も
そして株価という「名目価格」も
膨らむのは必然

最高値におびえて
現金を抱え続けることこそ
最もハイリスクな投資判断です…↓(2/6) Image
1989年のバブルと今の決定的な違いは
利益の裏付け

当時は期待だけで膨らんだ泡でしたが
2026年の今は
AIが企業の「純利益」を
物理的に押し上げる実利フェーズ

企業の稼ぐ力(ROE)は
当時と比較にならないほど強固です

価格ではなく「中身」を見れば
今の株価はまだ妥当な水準…↓(3/6)
Read 7 tweets
Apr 17
I’m leaving MIT and not continuing into my PhD. AI is coming too fast for humans to keep up.

But there might be a way: I realized digital humans are more possible than most think. With capable AI researchers helping, maybe for $10B, maybe in less than 10 years, on 50k H100s. Image
Running a human brain might need only ~50,000 H100 GPUs. xAI already has 200,000+ H100s or better.

To anchor the discussion, I did some very rough napkin math: Under fairly pessimistic assumptions using current high-resolution neurons (eg Hodgkin-Huxley), multi-state synapses, a human brain might be in reach of ~600 exaFLOP/s of compute, 700 GB memory storage per GPU, and 24 GB/s interconnect bandwidth. That's already in reach for today's clusters!

If much simpler neuron models (eg Leaky-Integrate-and-Fire) are enough--which needs more research to be empirically determined--then a human brain might be as cheap as ~2-3 petaFLOP/s. That's nearly a single H100 at FP16. (Memory and interconnect are likely tighter constraints.)

But what neurons to run? What parameters? What connectivity?
Hence data generation is the actual bottleneck with many problems to solve: We need hundreds of next-gen microscopes running for years. Automated large-scale tissue collection and staining.

~20x Expansion microscopy with thorough molecular staining of 30+ receptors, neurotransmitters, and neuropeptides. X-ray microscopy to eventually image a whole human brain in less than a year.

Whole-brain functional imaging scopes able to image brain activity across worm and fish brains to crack structure-to-function translation.

Also we'll need structure-to-function prediction models, proofreading models, rigorous benchmarks, and thorough animal emulations as proof-of-concept.Image
Read 7 tweets
Apr 17
Staying informed about common online scams is an important part of digital ownership, especially during periods when phishing attempts are more active across the ecosystem.

We want to make sure our community have the absolute best guidance on this, so here is a quick reminder on what Ledger will NEVER do. 👇
🚩 Ledger will never call you on the phone
🚩 Ledger will never DM you first.
Read 5 tweets
Apr 17
A new Scientific Reports study adds an important nuance to the long COVID conversation. The biggest difference was not between people with PCC and without PCC, but between uninfected people and everyone who had recovered from SARS2🧵
Long COVID may be part of a broader post-infectious biological spectrum, where symptomatic PCC represents the more clinically visible end of a continuous dysregulation rather than a completely separate category.
That matters, because a lot of people still think in very rigid categories here. But instead of two clean boxes - recovered vs long COVID - the biology may look more like a continuum.
Read 17 tweets
Apr 17
🧵 Ecco cosa si dice negli eventi organizzati dall'ambasciata russa in Italia.

"Siamo pronti all'escalation, prima con attacchi convenzionali nelle maggiori città europee, poi con l'impiego di armi nucleari". "Siamo pronti a punire l'Europa".

Fatemi dire un paio di cose.

1/➡️
1) Questi sono dei pagliacci.

Non bisogna spaventarsi, perché fanno scaremongering da quattro soldi. Ero indeciso se pubblicare il video o meno, perché la diffusione delle minacce è ciò che vogliono.

Ma lo ho caricato perché non possiamo accettare questo linguaggio.

2/➡️
Questi buffoni non possono dire cose così gravi senza subirne le conseguenze. In un Paese normale l'ambasciatore russo verrebbe convocato e cacciato via a calci nel culo, e tutti i "centri culturali" russi e filorussi verrebbero chiusi all'istante.

3/➡️
Read 15 tweets
Apr 17
Anthropic has been quietly rolling out a big change.

Businesses can no longer buy Claude subscriptions. API access only.

Enterprise got the call first. Here's what it means for your team 🧵 Image
Why now? The math stopped working.

One dev tracked 10 billion tokens across 8 months on a $100/month Max plan. That's $15,000 in API-equivalent value for $800 paid.

Anthropic absorbed those losses to grow Claude Code. With an IPO reportedly on the way, the subsidy was never going to last.Image
What happens next is already happening.

Engineers expensing personal Claude subscriptions on company cards. Managers buying five at a time. Entire orgs handing out cards so every dev can expense their own.

No SSO. No audit trail. When the CISO asks, there's no good answer. Image
Read 7 tweets
Apr 17
Just submitted a response to the NASA RFI on Lunar Power. It was a lot of fun doing the hardware analysis.

I think that beaming power from ground stations to the Moon is a great way to get shots on goal quickly, to provide power to survive the night, and to support assets anywhere on the side of the Moon that's easy to see!

Thread with some key figures below.
These two figures show where, on the Lunar south pole, you endure periods of Earth and solar blackout respectively.

In general, everywhere on the moon experiences a 350 hour freezing night. But near the poles, there are a few mountains where the sun almost always shines. During the Lunar winter, though, these areas always endure at least five days of shade, due in part to mutual shading. So pure solar + batteries is tough because very large batteries are needed.

OTOH, about 40% of the Moon can always see the Earth and another 20% can see it sometimes, in the Terminator region where Earth rises and sets over a four week period. Very beautiful looking! And in the boundary between these areas, there are a few islands where the Earth, or at least the parts of the Earth with power transmission arrays, never set.

The closest to the pole, on either pole, is Malapert Massif, but there are a few other areas nearby which are also interesting.Image
Image
There are some interesting trades between array design and power spot shape on the Moon. But probably the best way to do it is with a small, high power water cooled transmission array on Earth feeding a much broader spot on the Moon, which will support power over about 10 km. Anywhere you need power, just hang out a flexible rectenna array of the appropriate size, point it at the Earth, and you're good to go!Image
Image
Read 6 tweets
Apr 17
Lo que encontramos auditando la API de la ONPE — OpenElection Perú
Somos OpenElection, unn iniciativa de EV-Resilience independiente que construyó un sistema de conteo paralelo ciudadano. Descargamos y almacenamos los datos de 85,451 mesas de votación directamente de la API de la ONPE. Esto es lo que encontramos. 👇
HALLAZGO 1: El contador de ONPE va adelante de los datos verificables.
ONPE reporta 93.35% contabilizado (86,601 mesas).
Nosotros, consultando su propia API mesa por mesa, solo podemos verificar 85,451 mesas.
Hay 1,049 mesas que ONPE ya contó pero cuyos datos NO están disponibles en su API.
Esto significa que ONPE actualiza su contador público ANTES de publicar la metadata individual. ¿El problema? Nadie externo puede verificar esas 1,049 mesas. En una elección donde el 2do y 3er lugar están separados por ~25,000 votos, esto son ~180,000 votos sin verificación pública.
Read 9 tweets
Apr 17
While everyone is celebrating the rally someone just dropped $11M on $SPY puts.

Here's what I'm seeing. 🧵
$SPY just rallied 13% in 13 days off the lows.

Last year after a similar explosive move the market went sideways and slightly red before continuing higher.

History doesn't repeat but it rhymes Image
@AionAnalytics probabilistic outlook confirms it.

Crash detection 0.0%. Models 4/5 bull. Stress at 0.

But breadth is only 32%.

That's what's keeping the near term choppy.

Cone is flat before expanding higher. Image
Read 8 tweets
Apr 17
📣GREAT NEWS📣 Just spoke to Hill champions: your hundreds of calls & emails are making such a difference, they've extended deadline for Senator sign-on to #FundLongCOVID Dear Colleague letter to MONDAY APRIL 20 10am ET! More @LCCampaign details incoming, senators now signed: 1/x
@LCCampaign Along with FY27 #FundLongCOVID letter leads @SenMarkey @SenTimKaine @SenDuckworth, these senators have now signed on too: @Sen_Alsobrooks, @SenBooker, @SenAmyKlobuchar, @SenatorLujan, @SenAlexPadilla, @SenAdamSchiff, @SenTinaSmith, @SenWarren, @SenPeterWelch, & @SenWhitehouse 2/x
@LCCampaign @SenMarkey @SenTimKaine @SenDuckworth @Sen_Alsobrooks @SenBooker @SenAmyKlobuchar @SenatorLujan @SenAlexPadilla @SenAdamSchiff @SenTinaSmith @SenWarren @SenPeterWelch @SenWhitehouse 📣📣📣#LongCOVID Community, with deadline extended, let's keep the emails & calls going! These Senators signed the FY26 #FundLongCOVID letter last year, but haven't yet this year: @gillibrandny, @SenatorAndyKim, @SenatorWarnock, @RonWyden. Let's try & grow the list for FY27! 3/x
Read 4 tweets
Apr 17
Internet está lleno de tonterías pero también está repleto de webs maravillosas.

Aquí tienes sitios web (🔖 Imperdibles) que deberías conocer... Image
》Internet Live Stats

ENLACE ➜

Observe Internet a medida que crece en tiempo real y controle el uso de las redes sociales: usuarios de Internet, sitios web, publicaciones de blogs, Facebook, Google+, Twitter y Pinterest.internetlivestats.com
》Radio Garden

ENLACE ➜

Explora la radio en vivo girando el globo y buscando la ubicación que quieras.radio.garden
Read 22 tweets
Apr 17
A Universidade Católica pode formar pioneiros de um novo humanismo no contexto da revolução digital. É um serviço à verdade e a toda a humanidade. Sem este esforço educativo, a adaptação passiva às lógicas dominantes será confundida com competência, e a perda de liberdade com progresso. #ViagemApostólica #Camarões
Os sistemas de #InteligênciaArtificial moldam cada vez mais profundamente os nossos ambientes mentais e sociais. Tal como qualquer grande transformação histórica, também esta requer não só competências técnicas, mas uma formação humanística capaz de tornar visíveis as lógicas económicas, os preconceitos incorporados e as formas de poder que influenciam a perceção do real.
Nos ambientes digitais, construídos para persuadir, a interação é otimizada a ponto de tornar supérfluo o encontro real; a alteridade das pessoas de carne e osso é neutralizada e a relação reduzida a uma resposta funcional. Caríssimos, vós, pelo contrário, sois pessoas reais! Também a criação tem um corpo, uma respiração, uma vida a ser ouvida e a ser guardada.
Read 4 tweets
Apr 17
The Catholic University can form pioneers of a new humanism in the context of the digital revolution. This is a service to the truth and to all humanity. Without this demanding educational effort, passive adaptation to dominant paradigms will be mistaken for competence, and the loss of freedom for progress. #ApostolicJourney #Cameroon
#ArtificialIntelligence systems increasingly shape and permeate our mentality and social environments. Like every great historical transformation, this too calls not only for technical competence, but also for a humanistic formation capable of making visible the logic behind economics, embedded biases and forms of power that shape our perception of reality.
Within digital environments — structured to persuade — interaction is optimized to the point of rendering a real encounter superfluous; the otherness of persons in the flesh is neutralized, and relationships are reduced to functional responses. Dear friends, you, however, are real persons! Creation itself has a body, a breath, a life to be listened to and safeguarded.
Read 4 tweets