~ The McCairn Protocol ~
(also called the Edogawa-McCairn Protocol)
• is an experimental, two-part treatment approach developed or promoted by neuroscientist Dr. Kevin McCairn, PhD, in collaboration with a hospital in Japan (Edogawa Hospital) & ran by Dr Kato
• It primarily targets symptoms associated with Long COVID & post-mRNA vaccine injury
• it focuses on issues like persistent spike protein, amyloid fibrin microclots, autoantibodies, inflammation, & related vascular/neurological damage edogawadfpa.com
2)
• The full protocol is typically an outpatient process spanning about 2 weeks at the Japanese facility, with pre-/post-testing (including microclot analysis via Thioflavin T staining & fluorescence microscopy through Synaptek Labs)
• Dr. McCairn’s work involves neuroscience research (previously on movement disorders like tics in primates) & analysis of blood samples for amyloid fibrils, abnormal clotting, & prion-like misfolding potentially linked to spike protein
• The protocol addresses what proponents call “spikeopathy” — persistent effects from SARS-CoV-2 or mRNA vaccines leading to microclots, endothelial damage, & chronic inflammation
• It is not a mainstream or FDA-approved treatment for these indications
• It is positioned as a proof-of-concept study with patient testimonials (e.g., dramatic improvements in energy, cognition, & function in some severe cases or similar)
• Efforts are underway to fund IRB-approved trials in the U.S. to study it more rigorously
• This protocol represents one investigational avenue in a broader field of microclot & spike-related research
• Unlike standard plasmapheresis (which replaces plasma with donor plasma or albumin), DFPA uses filtration to retain most of the patient’s own plasma while targeting specific larger molecules/pathological elements
~ Goal:
• Physically remove circulating microclots (often amyloid-positive fibrin structures) & inflammatory triggers that may impair microcirculation, contributing to fatigue, brain fog, etc
@forallcurious Possibility of Cold Neutrino Ejection from Black Holes & Dark Matter Production
Touches many active areas of theoretical physics — primordial black holes (PBHs), Hawking radiation, sterile neutrinos, dark matter — not a standard model prediction but theoretically possible...
@forallcurious These emissions could be sterile neutrinos interacting weakly with Standard Model sector.
Sterile neutrinos produced at low energies (cold) may escape observable universe w/o interacting, invisible to current detectors.
Sterile neutrino dark matter candidates evade detection.
@forallcurious PBHs slowly evaporate, releasing low-energy particles which are dark matter candidates (sterile neutrinos, axions) remaining in a separate “dark sector” or extra dimension.
PBHs may undergo final explosive bursts (Hawking explosion) producing high-energy particles & dark matter.
This was the exact game state everyone feared for England.
They possess an abundance of profiles designed to penetrate the box with carries or off-ball runs, but they completely lack a natural manipulator
THREAD.🧵
Attacking a low block with Declan Rice and Jude Bellingham operating between the lines is a profile mismatch.
Neither is naturally suited to consistently receiving in tight spaces, turning under pressure, or combining quickly in the final third.
Credit to Carlos Queiroz.
Ghana's defensive application was elite.
They maintained a highly disciplined, passive 4-1-4-1/4-5-1 block that completely compressed space and slowed England's possession tempo.
Yesterday: Faecalibacterium prausnitzii depleted in Parkinson's disease.
Today: the same bacterium, a different brain disease ... Alzheimer's.
In Alzheimer's, its depletion triggers a completely different chain — one that targets the blood-brain barrier and drives neuroinflammation from the inside.
Here's the science 👇
#Alzheimers #GutBrainAxis
F. prausnitzii has been identified as depleted in Alzheimer's patients across multiple human cohort studies.
Ueda et al. 2021 (Cell Reports Medicine) identified specific F. prausnitzii strains as candidate targets for gut microbiome-based intervention in Alzheimer's-type dementia.
Depletion correlates with worse MMSE cognitive scores — the standard clinical test for dementia severity.
The AD mechanism is different from Parkinson's.
↓ F. prausnitzii
→ ↓ butyrate
→ HDAC inhibition lost
→ NF-kB pathway hyperactivated in microglia
→ TNF-alpha, IL-1beta, IL-6 elevation
→ accelerated amyloid-beta deposition
→ tau hyperphosphorylation
Butyrate also maintains claudin-5, the blood-brain barrier tight junction protein. When F. prausnitzii falls, the BBB becomes permeable to peripheral inflammation.
Trump has turned the White House into a 24/7 corruption operation. This is a national crisis.
Trump thinks the public will stop paying attention.
So I went to the Senate floor to call his bluff. I told the ENTIRE STORY of his 500 days of corruption.
1/ Here it is - in one🧵
DATE OF CORRUPTION: April 7, 2025
Donald Trump, one of the biggest crypto players in the world, declares we will no longer be enforcing our laws against the crypto industry.
Active fraud investigations are shut down. The entire crypto enforcement team at DOJ is fired.
DATE OF CORRUPTION: September 23, 2026
Border Czar Tom Homan is caught by FBI agents taking a bribe in exchange for federal contracts. The FBI has video footage of Homan accepting a big bag of cash.
Trump kills the FBI investigation, and Homan gets a job in the administration.
Autism is a mitochondrial disorder - and restoring their function can improve it, demonstrated beautifully in a recent trial.
(🧵1/8)
Mitochondrial dysfunction is any abnormality in this organelle's ability to generate energy or other substrates.
Depending on the criteria, anywhere from 5% up to 90% (in this study) of people with autism spectrum disorders suffer from some form of mitochondrial dysfunction.
Thus, the goal in this study was to identify that subset and treat accordingly.
This was done with the use of a mitochondrial targeted supplement.
It contained various essential vitamins and minerals,
as well as other nutrients like carnitine and CoQ10 that are also important for mitochondrial metabolism.
You’ll know I won the lottery when I disappear from this website and buy this $830,000 home in Prior Lake, MN designed by John Howe, protégé of Frank Lloyd Wright (yes I am a basic bitch)
Come the fuck on
Kitchen needs an update but I’d be honored to do it
I took a scientific approach, you can too. In this post I've shared everything I did to reverse my skin age and how you can do the same.
+ my skin protocol
+ how skin measurement works
+ how to start
+ how to track
🧵
Before I dive in, it’s important to note that facial aging is made up of MANY different parts.
Aging affects a lot…
For example:
- Bone structure
- Collagen
- Hydration
- Elasticity
- Fat
- Placement of tissue (gravity)
This post focuses on specific key facial aging markers, and it does not cover them all.
So, I am not saying I look 21 yrs old... or that I am 21 yrs old according to all skin markers - just the specific key skin markers that multi-spectral imaging can measure. And according to those 8 markers, my skin age is 21 years old.
It’s also worth noting that five years ago, I was eating McDonald's daily and did not do anything specific for my skin…
Then I met @bryan_johnson , we started our health scientific experiment together, and I started to change my core habits… which no doubt had a major impact on my overall aging.
Here’s the earliest face scan I can find.
> at age 27, my skin was age 26
> now age 30, my skin is age 21
This means that in 3 years, instead of accumulating 3 years of skin age, I reversed my skin-age by 5 years.
How does face measurement work?
This device uses multi-spectral-imaging. It uses standardized visible, polarized, and UV lighting to assess surface and subsurface skin features. It is a well-validated skin-analysis tool.
This measurement does a lot, but not everything.
What it DOES measure:
+ spots
+ pores
+ wrinkles
+ texture
+ UV spots
+ brown spots
+ red areas
+ porphyrins
It does NOT measure:
+ collagen
+ elasticity of skin
+ structural bone
+ plenty else
Currently, there’s no easy way to measure things like collagen and bone loss.
Last week, U.S. officials called Cuba's recent economic reform package, its most dramatic in 60 years (at least on paper), "superficial smoke signals."
Today's SDN listings may have already been in works, but timing amounts to an additional snub.
I and others have asked many Qs about the reforms:
How will they be sequenced?
Will there be follow through or are they meant to buy time?
Can they work w/o political opening or accomodation w DC?
Will they just empower new elite but impoverish majority?
But rather than saying "Ok - there are some things that look like progress in right direction on paper (private sector expansion etc), but we need to see follow through on X, clarity on Y, and more on the political front," Washington is basically saying "Ask me if I care."
وقال لي إني خلال 6 أشهر ممكن ما أحتاج راتب أصلًا مرة ثانية.
هذه هي 7 البرومبتات اللي كانت وراء خطة خروجي من الوظيفة:
الواقع القاسي (مراجعة صادمة):
1. "تصرف كأنك خبير استراتيجيات مالية. باستخدام دخلي [المبلغ]، وتكاليفي الثابتة [القائمة]، ودخلي الجانبي الحالي [المبلغ] — وضّح لي وضعي المالي الحقيقي. وأرِني أكبر ثلاث فرص أنا أتجاهلها، وأهم تغيير واحد لازم أسويه هذا الشهر عشان أقرب من الحرية المالية."
👉 أغلب الناس يتجنبون هذا النوع من الحوار. كلود ما يحكم عليك، بس يعطيك الحقيقة كما هي.
مُحدِّد المصاريف:
2. "حلّل مصاريفي الشهرية: [الصقها هنا]. حدّد كل دفعة أدفعها من باب العادة وليس الضرورة. احسب بالضبط كم أقدر أوفّر شهريًا إذا ألغيتها. ثم ورّني كيف أوجه هذا المال لبناء دخل ثاني."
👉 أغلب الناس يكتشفون هنا من 150 إلى 300 يورو خلال أقل من 10 دقائق.
Ex-Ukrainian FM, Kuleba: Trump's G7 softening on Ukraine is not a real shift. Right words at the right table, nothing more. Before the summit he spoke to Putin and called him wonderful.
Every change in tone is situational. This is performance for the camera. 1/
Kuleba: Trump desperately needs a big foreign policy victory. There are only two places left on Earth where he can get one, Cuba and Ukraine.
That is why American efforts on Ukraine will intensify. Not from conviction — from necessity. Trump needs a win he can sell. 2/
Kuleba: One test tells you everything. Kushner is heading to Moscow again. If before Moscow he stops in Kyiv, something is genuinely changing inside the American system.
If he flies straight past, same pattern, same priorities, same war. Watch the itinerary, not the rhetoric. 3X
El problema fue que nunca se convirtió en contenido útil.
Entonces probé un flujo de trabajo diferente con Gamma 👇
Las noticias sobre IA se mueven rápido.
Nuevos modelos. Artículos de investigación. Rondas de financiación. Lanzamientos de productos.
En lugar de convertir todo en hilos, convertí las actualizaciones de IA de una semana en un resumen visual.
Mensaje: "Cree un resumen semanal de noticias sobre IA para creadores. Resuma las 5 actualizaciones principales, explique por qué cada una es importante, agregue conclusiones simples y organícelas como una presentación visual limpia".
Luego abrí @GammaApp
Gamma ayudó a convertir las noticias en:
• Un resumen semanal limpio
• Explicaciones sencillas
• Secciones visuales
• Conclusiones clave
• Información centrada en el creador
En lugar de mirar una página en blanco, tenía una historia estructurada lista para editar.
ok gang.... it looks like the Anthropic Claude team have removed the flag on my account and my CVP is working!
ok cool, now if you have followed me long enough you know i wrote my own ones of these manually a long time ago. but this is a good example of how to use an LLM to maybe help people learn, how to ensure consistency of approach and method to testing and for science!
I'm just generating an html document. then let's get it to give as a training document right!
THREAD - OL et le "Kang take over" - uniquement sur base du communiqué
1. Il y a 2 niveaux de dette à rappeler:
-Eagle Bidco (holding) dette : Ares (547 M$)
-OL SASU (le club) dette : "Goldman Sachs", MUFG, MetLife
Deux structures séparées. Ares n’est pas dans la dette du club. Goldman/MUFG/MetLife ne sont pas créanciers d’Eagle Bidco.
1 bis. Hiérarchie des dettes dans Eagle:
_Goldman/MUFG/MetLife sur OL SASU (dettes seniors garanties par le stade et les actifs du club)
_Ares sur Eagle Bidco (notes sécurisées par les participations dans les clubs)
_Dettes subordonnées intragroupes (Textor, Botafogo, RWDM…)
232,6 M€ correspondent intragroupes : prêt Eagle Bidco de 87,3 M€, avances EFH de 35,7 M€, avance Textor de 17,9 M€ autres dettes Botafogo/RWDM
2. La vente forcée par l’administrateur judiciaire
Cork Gully, administrateur d’Eagle Bidco, vend les actifs pour rembourser les créanciers. Il cède 87,78 % d’EFG pour USD 30M. Prix par action : USD 0,19.
Prix qui reflète la détresse du vendeur, pas la valeur réelle du club