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SQ MTX offers the advantage of delivering 100% of the med to the patient.
Split dose oral MTX also increase bioavailability >28% over single dose.
Also important to make sure you escalate the dose of MTX up to 20-25mg/wk.
#ACR19
Split dose oral MTX also increase bioavailability >28% over single dose.
Also important to make sure you escalate the dose of MTX up to 20-25mg/wk.
#ACR19
2/3 of patients don’t achieve low disease activity or remission on MTX alone. These pts need another agent.
Keeping them on MTX increases the efficacy of some biologics (TNFi, RTX) and helps prevent drug-blocking antibodies.
#ACR19
Keeping them on MTX increases the efficacy of some biologics (TNFi, RTX) and helps prevent drug-blocking antibodies.
#ACR19
