Discover and read the best of Twitter Threads about #AHA20
Most recents (16)
➡️Yes, this combo improved Sxs & reduced CVD death & hosp rates (click here)
💯Correct!
⚡️The HYD/ISDN combo was tested in the A-HeFT trial in an all-AA population with HFrEF.
⚡️More than 80% also had T2D & ~34% had renal insufficiency.
⭐️The vasodilator combo showed improvements in Sxs & reductions in hosp & CVD death rates.
⚡️The HYD/ISDN combo was tested in the A-HeFT trial in an all-AA population with HFrEF.
⚡️More than 80% also had T2D & ~34% had renal insufficiency.
⭐️The vasodilator combo showed improvements in Sxs & reductions in hosp & CVD death rates.
3 recently published studies show pts with HF, T2D, & CKD would benefit from a drug in which class?
Tons of chatter about the new prescription omega 3 data coming forth. Lots of takes about the study designs, n3 formulations, differences across populations, variation in comparator groups. All important ?- but I think there's a bigger 🐘in the room. #cardiotwitter #lipids #AHA20
Intervening with n3 fatty acids is unlike other drugs bc they are a nutrient. There is no placebo for n3s in the sense that:
1) you have questions about what is the ideal comparator; typically isocaloric oil.
2) you don't have an unexposed group - there are endogenous levels.
1) you have questions about what is the ideal comparator; typically isocaloric oil.
2) you don't have an unexposed group - there are endogenous levels.
There are numerous reasons for n3 enthusiasm, but playing by evidence hierarchy, the top reason is that meta-analyses of cohorts demonstrate that higher blood levels of n3s result in reduced risk of fatal CHD jamanetwork.com/journals/jamai…
NEJM published 2 RCTs of #AFib ablation vs AF drugs.
The rub was that the ablation was done EARLY in the course.
Practice had been to try drugs first then do ablation.
EARLY AF and STOP AF studied the procedure early.
#AHA20 Thread and my column >>
The rub was that the ablation was done EARLY in the course.
Practice had been to try drugs first then do ablation.
EARLY AF and STOP AF studied the procedure early.
#AHA20 Thread and my column >>
Both trials used the Medtronic cryoballoon system.
Medtronic participated in funding both trials.
STOP AF was 100% an industry trial. See pic.
Early AF had funding from many other sources
Medtronic participated in funding both trials.
STOP AF was 100% an industry trial. See pic.
Early AF had funding from many other sources
Background -- numerous trials have shown that AF ablation using different techniques (freezing or burning) can reduce AF episodes relative to meds.
In CABANA -- the largest outcome trial, AF ablation reduced AF but had no sig effect on clinical outcomes like stroke or death.
In CABANA -- the largest outcome trial, AF ablation reduced AF but had no sig effect on clinical outcomes like stroke or death.
Wonderful talk at #AHA10 @MarilynCipolla on #preeclampsia and the Brain #neuroobstetrics #cardioobstetrics @uvmvermont @MaryCushmanMD
🧠Preeclampsia is vascular disorder
🧠Preeclampsia defined below @acog
🧠Once you have PE, greater 🫀 events, HTN, DM
🧠 But also BRAIN effects
🧠Preeclampsia is vascular disorder
🧠Preeclampsia defined below @acog
🧠Once you have PE, greater 🫀 events, HTN, DM
🧠 But also BRAIN effects
#AHA20 #preeclampsia
🤰Preeclampsia is an exaggerated response of pregnancy induced inflammation, hyperlipidemia and hypercoagulation
⬆️ risk of:
🧠seizures
🧠stroke
🧠cognitive decline
🤰Preeclampsia is an exaggerated response of pregnancy induced inflammation, hyperlipidemia and hypercoagulation
⬆️ risk of:
🧠seizures
🧠stroke
🧠cognitive decline
Dr. Peter Rothwell: Paul Dudley White lecture & reminds us that PDW was ahead of his time, believing lifestyle was key. The Pathway along the Charles River is named after him #AHA20
Best quote " I wish we could do something useful with tobacco- like making fertilizer out of it"
Best quote " I wish we could do something useful with tobacco- like making fertilizer out of it"
Profound effect BP on Risk of Stroke #AHA20
🧠🫀 #BloodPressure... #PDWLecture
16 Fold risk association with mean BP and stroke
🧠🫀 #BloodPressure... #PDWLecture
16 Fold risk association with mean BP and stroke
Treatment of HTN decreased risk of recurrent stroke: Important work from Dr. Rothwell @UniofOxford #AHA20 @AHAMeetings #PDWLecture
#mSToPs Study presented at #AHA20 #LBCT @SteveSteinhubl @EricTopol
💫Lifetime risk of Afib ⬆️ (.40%)
💥Risk of #Afib is stroke but also Heart Failure and CV Mortality is even ⬆️⬆️
🥅 was to assess ECG patch in diagnosis of Afib & improve outcomes
💫Lifetime risk of Afib ⬆️ (.40%)
💥Risk of #Afib is stroke but also Heart Failure and CV Mortality is even ⬆️⬆️
🥅 was to assess ECG patch in diagnosis of Afib & improve outcomes
Dr. David Williams speaking at #AHA20
💸Pay gap for Black Americans is 59 cents vs $1 for White Americans
🛑Same as 1978!
Racial differences haven't changed in all this time
At every level of education, gap persists: income and education matter but race overrides this
💸Pay gap for Black Americans is 59 cents vs $1 for White Americans
🛑Same as 1978!
Racial differences haven't changed in all this time
At every level of education, gap persists: income and education matter but race overrides this
Racial Segregation is real #AHA20 and was part of racial regulation
💔2/3 of all Black Americans live in very low opportunity neighborhoods
💔This access to opportunity (or lack thereof) is a driver of racial ethnic differences
💔2/3 of all Black Americans live in very low opportunity neighborhoods
💔This access to opportunity (or lack thereof) is a driver of racial ethnic differences
The consequences of lack of opportunities increases all level of stressors and the consequences are real:
▶️Accelerated aging
▶️Premature aging
▶️Earlier onset of chronic diseases
#AHA20 @AHAMeetings #racism #racisminmedicine
▶️Accelerated aging
▶️Premature aging
▶️Earlier onset of chronic diseases
#AHA20 @AHAMeetings #racism #racisminmedicine
@AnastasiaSMihai @loriannpeterso1 & I will be presenting Poster #1432 at #AHA20. It will be presented at 9am CT (soon) but before it is, I want to thank you all for filling out my survey on #cardioTwitter because this is what our poster is based on.
We wanted to find our how you measure #bloodpressure & how reliable you felt your clinical BPs were. I regret to inform you despite you liking your BP reads & trusting them, most of you don't check it correctly @HeartBobH #AHA20 Thanks to @Heart_SCCT @ASPCardio @HBPRCA for help
For those interested in some science after much excitement 🇺🇸🇺🇸🇺🇸 this past week, thrilled to share our latest in @CircAHA (simultaneous pub w/ #AHA20)
Why do women with premature menopause have ⬆️ risk of CVD?
ahajournals.org/doi/abs/10.116…
👇 (thread)
Why do women with premature menopause have ⬆️ risk of CVD?
ahajournals.org/doi/abs/10.116…
👇 (thread)
We previously described diverse accelerated cardiovascular aging in women with premature menopause (jamanetwork.com/journals/jama/…), a “risk-enhancing factor” for ASCVD
Mechanisms underlying these associations remain unclear 🤔
Mechanisms underlying these associations remain unclear 🤔
In genome-wide association studies of age at natural menopause (nature.com/articles/ng.34…), ~2/3 of identified genetic loci map to DNA damage repair enzymes
➡️ implies women with natural premature menopause may be genetically predisposed to accumulate DNA mutations 🧬🧬
➡️ implies women with natural premature menopause may be genetically predisposed to accumulate DNA mutations 🧬🧬
Following up on @EADHistory's thread we want to share our work in Marketing the History Major from #AHA20 #s279. From 2013 to 2016 we had a 27% decline in major numbers; since 2016 we are up 12% for majors and up 20% when you include minors with majors. 1/19
We currently have the most juniors we've had since 2013. From 2013 to 2016 there were 39% fewer HIST majors reaching junior standing @UofOklahoma. Since 2016, there are 42% more HIST majors reaching junior standing. We're adding (avg) 2+ HIST grads, 9 majors every spring 2/19
Our work in reversing this decline has 3 aspects: curricular changes; supporting professional advising; and targeted data outreach.
Curricular: in 2009 we added 2 majors-only courses to help create community among our students + bolster their skills. 3/19
Curricular: in 2009 we added 2 majors-only courses to help create community among our students + bolster their skills. 3/19
I was part of the #AHA20 #s279 on Marketing the History major. It was a great conversation w/ Paul Deslandes (Vermont), Sarah Olzawski (@OUHistDept), Darién Davis (Middlebury), and @justin_behrend (@GeneseoHistory). Here’s a recap of @LMU_History's efforts ... 1/26
At @LMU_History, we peaked in our number of majors in spring 2011, but then saw a decline of 60%+ – a function of national trends, revisions to our University Core Curriculum that drastically cut history’s presence in it, and the creation of new majors in @LMUBellarmine. 2/26
But after hitting our low in fall 2017, we’ve seen an increase of 35% in majors, an increase of 120% in minors, and strong enrollments across all courses. How did we reverse course? A combination of curricular reform, programming and publicity efforts, and recruitment. 3/26
#Iran's Ayatollah Ali Khamenei stated in 2015 that "black people are oppressed, disrespected & humiliated" in the U.S. Hey all you flag-waving #American
#patriots, are you gonna let him get away with that!? Why not support #reparations to prove him wrong? timesofisrael.com/iranian-leader…
#patriots, are you gonna let him get away with that!? Why not support #reparations to prove him wrong? timesofisrael.com/iranian-leader…
And, yes, Khamenei is a hypocrite & has no moral authority to condemn the violent suppression of "minorities" when #Baha'is & other religious minorities in #Iran are systematically killed, jailed, excluded from society, denied passports, etc. But he ain't wrong about Black people
As #Twitterstorians and #BlkTwitterstorians know, it was this kind of geopolitical propaganda from the #USSR that shamed U.S. Cold War liberals into supporting the end of Jim Crow (long before U.S. popular opinion turned on this issue). #Reparations may come the same way. #AHA20
My next (and sadly my last) #AHA20 livetweet for the #sschat community bright & early on a Sunday morning....
"The Role of History Educators in a Time of Crisis" with @chriscmartell @HSGlobalHistory @TrevorGetz4
What *needs* to happen in history education?
"The Role of History Educators in a Time of Crisis" with @chriscmartell @HSGlobalHistory @TrevorGetz4
What *needs* to happen in history education?
@chriscmartell @HSGlobalHistory @TrevorGetz4 @chriscmartell is up first: focus on building bridges between historians & history teachers
a few thousand self-identified historians/professors in US
BUT
1.1 million elementary generalists are often overlooked when considering 'who teaches history'
a few thousand self-identified historians/professors in US
BUT
1.1 million elementary generalists are often overlooked when considering 'who teaches history'
@chriscmartell @HSGlobalHistory @TrevorGetz4 18% of the almost 300K undergrad history majors report they wish to become K-12 teachers!
Decline of history majors is bad news for public ed
3/x
Decline of history majors is bad news for public ed
3/x
Settling in for what looks like a great History of Capitalism panel at #AHA20.
Amy Edwards is offering a fascinating look at the role the UK media played in the spread of Thatcher’s “popular capitalism” — Page Three girls promoting stocks, a dumbed down “Money Page” to build up investors, BBC programs like Money Spinner, etc. #AHA20
Edwards talks about the spread of financial game shows and board games — including this one from Andrew Lloyd Webber! #AHA20
Getting ready for #s1 at #AHA20 "Humanities PhDs Beyond the Academy: The Employers Perspective," featuring employers who have hired @ACLS1919 public fellows. #AHACareerDiversity
@ACLS1919 If you don't know about the @ACLS1919 Public Fellows program, you should definitely check it out. This is one of the flagship #CareerDiversity opportunities out there. 2020 applications will open soon.
acls.org/programs/publi…
acls.org/programs/publi…
@ACLS1919 The program places humanities PhDs in 2-year fellowships at nonprofits, govt, business, etc. Designed to benefit recent graduates #WithAPhD and provide a public demonstration of the value that humanists bring to a variety of careers.
#s1 #AHA20 #AHACareerDiversity
#s1 #AHA20 #AHACareerDiversity
Fighting through a brutal cold to get ready for #AHA20.
I'll be taking part in two panels, both on Sunday.
I'll be taking part in two panels, both on Sunday.
First up, a session on Historians and Presidential Misconduct with Jim Banner, Kathy Olmsted and @JeremiSuri, drawn from the updated edited collection PRESIDENTIAL MISCONDUCT to which we all contributed.
aha.confex.com/aha/2020/webpr…
#AHA20
aha.confex.com/aha/2020/webpr…
#AHA20
@JeremiSuri Then in the afternoon, I have the honor of chairing what should be a fascinating panel on The Politics of Guns in the Late Twentieth Century.
Papers by Clay Howard, Carl Babitzke and @JulioCapoJr with comments from the great @micnick11.
Come on out and see them! #AHA20
Papers by Clay Howard, Carl Babitzke and @JulioCapoJr with comments from the great @micnick11.
Come on out and see them! #AHA20
