Discover and read the best of Twitter Threads about #Achalasia

Most recents (3)

4 years and 9 months ago, I undertook a moonshot to cure a disease that doctors call "incurable." It's called #Achalasia. Although there is no cure for Achalasia and no doctor in the world was even working on one, I gave myself 5 years to make it happen.

Thread.
(1/4) To hold myself accountable, @BillCarmody and I wrote about this "moonshot" in @Inc (inc.com/bill-carmody/p…).

Sounds ridiculous. However, the ignorance of an entrepreneur is a beautiful thing.
(2/4) I have written extensively about my journey here (phillipstutts.medium.com/my-personal-mo…), but I have not updated it in over a year - and boy, have there been some big changes... life-changing to be exact.
Read 5 tweets
Discussion from this past #TracingTuesday:

As many have noted, this tracing showed inadequate LES relaxation & no normal esophageal body peristalsis - the definition for #achalasia. There’s evidence of esophageal shortening in some swallows, causing pseudo-relaxation. (1/4)
This study does not clearly fall into any of 3 achalasia subtypes: no failed swallow, no PEP >30 mmHg, no spastic contractions (DL >4.5). Note the difference b/t true PEP (non-contractile, uniform pressurization) and this case, which has a clear distal contraction fragment. (2/4)
Although DL is normal throughout, if the former CFV metric is applied, the contraction front velocity is certainly high, suggesting simultaneous contractions. This highlights the limitation of using DL alone & importance of visual interpretation of peristaltic pattern. (3/4)
Read 4 tweets

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