Discover and read the best of Twitter Threads about #Aggregation

Most recents (4)

🚨 GET 15 AIRDROPS WITH ALMOST ZERO COST

- When I say zero cost it means the amount of money you still need to pay for the fees is less than 1% of the #airdrop you might get

- You probably have done these tasks before but its still gd idea to be a repeat user
#Alpha 🧵🕵️‍♂️⚡️🪂 Image
1/
- I strongly recommend not going for airdrop #farming and staying a genuine user, you don't wanna lose #airdrops for being flagged as a #hunter
- I suggest doing at least 2-3 #transactions on each product and keeping it +1K dollars, repeat the steps till you reach that amount
2/
- Most tasks are #Swaps and #Bridges so always changes the #network and even the #tokens you swap or bridge / The more network you do #transactions the better

- You can go from A to B then B to C .. C to D to the end OR A to C - C to F - F to B .... do it in random order✅
Read 14 tweets
Polysorbate 80, also present in Moderna C19 vac.
PS80 delays the inhibition of thermal aggregation process of insulin. Addition of PS80 leads to an increase in beta-sheet structure and concomitant altered morphology and ...
#betaamyloid
#protein
#aggregation
enhanced stability of the formed spherulites. This may impact safety and efficacy of the protein drugs product.
Read 7 tweets
Check out our latest paper on @biorxivpreprint!

Phosphorylation of the overlooked #tyrosine 310 regulates the structure, #aggregation, and #microtubule- and #lipid-binding properties of #Tau

biorxiv.org/content/10.110…

Short #thread!

#AcademicTwitter #biochemistry #threadstory
Tau misfolding and aggregation are implicated in tauopathies such as #Alzheimers and #PSP. Tau is extensively post-translationally modified and aberrant pattern of PTMs are found in disease. Tyrosine PTMs have received the least attention, especially Y310.
Tau has 5 tyrosines, and Y310 is in the crucial position within the aggregation-prone MT- and lipid-binding repeat domain. It compacts and folds into beta-sheet structure. We asked:

How would addition of bulky negatively charged phosphogroups to tyrosines impact Tau properties?
Read 14 tweets

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