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Small thread on why I think we will see a bigger outbreak of #monkeypox d/t #COVID19 .We know Covid causes T cell response suppression in some & also complement mediated injury leading to effective reduction in levels of complements (hypocomplementemia) ctd)@fitterhappierAJ ctd)
2/n We know for a fact that at least in kids the complement induced injury caused hypocomplementemia in young , this was one of the pathways of acute liver injury in some kids , if the complement system is exhausted
#monkeypox
doi: 10.1097/INF.0000000000002804. PMID: 32639461.
@medriva @VirusesImmunity @britsocimm @KunstJonas @ManojShukul @Kanupriya78 @kumarmanish9 @RonaldKlain @G_LaryeaAdjei @amrit_lohia 3/n We also know that #Covid causes direct infection of T cells and leads to lymphopenia , we need to understand that post #Covid the T lymphocytes arent there to save infection ctd) .
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