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Our paper is out! 😊
Showcasing the complexity of #mutationalsignatures
A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies @NatureCancer
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1/ nature.com/articles/s4301…
Showcasing the complexity of #mutationalsignatures
A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies @NatureCancer
👇
1/ nature.com/articles/s4301…
We compare and contrast components of analytical steps in signatures analysis and suggest a practical framework for seeking Mutational signatures in tens to hundreds of tumour samples.
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Applying these methods on 3107 WGS primary cancers of 21 organs reveals known signatures and nine previously undescribed rearrangement signatures.
Spot the workflow 👇
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Spot the workflow 👇
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