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1/ Happy to share our latest work out today in @Cancer_Cell – a single-cell dissection of the kidney cancer immune microenvironment that uncovers important immune circuitry in advanced disease stages @DanaFarber @DanaFarberNews @harvardmed @broadinstitute
cell.com/cancer-cell/fu…
cell.com/cancer-cell/fu…
2/ The immune microenvironment plays critical roles in controlling the progression of cancer and in response to immunotherapies, yet there are still key open questions regarding the immune cell composition, phenotypic states, and cellular interactions in kidney cancer
3/ To comprehensively dissect the immune microenvironment in kidney cancer, we performed scRNA-seq / scTCR-seq) on 164,722 individual cells from tumor and adjacent non-tumor tissue in patients with ccRCC across disease stages: early, locally advanced, and advanced/metastatic 
