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Delighted to introduce correspondence analysis of scRNAseq. We show CA of Freeman-Tukey residuals outperforms CA of the Pearson Residuals

corral: Single-cell RNA-seq dimension reduction, batch integration, and visualization with correspondence analysis
biorxiv.org/content/10.110…
Code to reproduce figures are available at github.com/laurenhsu1/cor….

Functions are available in the corral @bioconductor package. bioconductor.org/packages/relea…
Decomposition of the Pearson Residuals is Correspondence analysis.

It's nicely described by displayr.com/math-correspon… .

I also described it in a workshop presented at #Bioc2020 and #Bioc2021 conferences aedin.github.io/PCAworkshop/ar

Its fast and rapid to compute
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