Discover and read the best of Twitter Threads about #CAP21

Most recents (2)

Catching up on 🧬 “Understanding #NGS and Interpreting Reports for Oncologic Pathology” with Dr. @sabahkadri and Dr. Cecilia Yeung at #CAP21 @AMPath 👩🏻‍💻

Super useful talk with excellent case studies! Here are just a few takeaways 🧵⬇️ #MolecularPath_CEJ #Informatics_CEJ
🤔 Considerations in developing an NGS assay

📌 @Pathologists has NGS assay development tools regarding test design, validation, quality, and bioinformatics: cap.org/member-resourc…
📌 How much do you want to know? ➡️ what test is needed? (WGS vs WES vs targeted sequencing)

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🧬 NGS in a nutshell with Dr. Yeung

1️⃣ Library preparation (hybrid capture vs amplicon-based)

2️⃣ Sequence the fragments of DNA (cyclic reversible termination vs detection of chemical byproducts ⚡️ as single nucleotide is added)

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Read 15 tweets
🧬#MolecularPath “Selecting the Right Tool for the Job: Practical Considerations for the Application of Molecular Diagnostics Methods in SurgPath” with @LJTafeMD and Dr. Larissa Furtado

A few takeaways (just scratching the surface of this excellent talk!) ⬇️🧵#MolecularPath_CEJ Image
First up: Pre-analytical Considerations

Purposes of molecular oncology testing:

🔵 Diagnosis
🔵 Therapy response/management
🔵 Monitoring

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Considerations for molecular oncology testing:

🔵 Availability of specimens
🔵 Testing options: targets 🎯, analytical sensitivity, TAT ⏱, cost
🔵 Clinical scenario
🔵 NCCN guidelines

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Read 18 tweets

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