Discover and read the best of Twitter Threads about #CCR5
Most recents (2)
First Person Cured of #HIV, Timothy Ray Brown, Dies from #Cancer
weather.com/en-IN/india/he…
(📸: B A Raju/BCCL Chennai)
weather.com/en-IN/india/he…
(📸: B A Raju/BCCL Chennai)
- The first person cured of HIV, Timothy Ray Brown, has died from cancer.
- Brown, who was also known as "the Berlin patient", was given a bone marrow transplant from a donor who was naturally resistant to #HIV.
#TimothyRayBrown
- Brown, who was also known as "the Berlin patient", was given a bone marrow transplant from a donor who was naturally resistant to #HIV.
#TimothyRayBrown
- It meant he no longer needed anti-viral drugs and he remained free of the virus, which can lead to AIDS, for the rest of his life.
- The International AIDS Society said Brown gave the world hope that an HIV cure was possible.
#TimothyRayBrown
- The International AIDS Society said Brown gave the world hope that an HIV cure was possible.
#TimothyRayBrown
#Leronlimab is an antibody that blocks a cell receptor called CCR5. The #CCR5 receptor just happens to be a key doorway HIV uses to get inside a cell so that’s why we developed it as an HIV treatment. But the actual function of CCR5 inside our body is to direct cell movement and
Function. Breast, prostate, and a few other cancers co-opt the immune system to support their growth by using the CCR5 receptor to control cell movement and function. We were targeting that role of CCR5 to support cancer cell growth when COVID-19 hit. Our early signals of success
in breast cancer led us to believe we could impact the inflammation, or #cytokinestorm, that is killing patients with Covid-19 since it is the same cell movement and function controlled by CCR5 that is involved. And, as incredible as it sounds, I believe we got very lucky and
