Discover and read the best of Twitter Threads about #CICO
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Not mutually exclusive, but most people said they'd prefer seeing rather than joining a discussion to analyze THAT erythritol paper, and I have some airport hours ahead...
Here gođ§ľ.
In case you've been living under a rock, this is the paper:
nature.com/articles/s4159âŚ
Here gođ§ľ.
In case you've been living under a rock, this is the paper:
nature.com/articles/s4159âŚ
Relevant disclosures for interpreting my interpretation?
I'll speak more as a clinician clinician who sees many âŹď¸CVDrisk patients following a low-carb diet than as a healthy adult who follows a low-carb diet and occasionally consumes erythritol.
I'll speak more as a clinician clinician who sees many âŹď¸CVDrisk patients following a low-carb diet than as a healthy adult who follows a low-carb diet and occasionally consumes erythritol.
Things I liked about the paper = â
ď¸.
Things I didn't like (and matter) = â ď¸
Things I didn't like (and are nitpicking) = đ§.
đŠ¸[] = blood concentration.
CVD = CardioVascular Disease.
MACE = Major Adverse Cardiovascular Events.
Why we "liked" erythritol in the first place?
Things I didn't like (and matter) = â ď¸
Things I didn't like (and are nitpicking) = đ§.
đŠ¸[] = blood concentration.
CVD = CardioVascular Disease.
MACE = Major Adverse Cardiovascular Events.
Why we "liked" erythritol in the first place?
â ď¸NEW PAPERâ ď¸
@AJCNutrition with: Mark Pereria, Cara Ebbeling, @LuciaAronica & @davidludwigmd
doi.org/10.1016/j.ajcnâŚ
With many of my favorite things:
1) Open Science.
2)Critical analysis of high quality research.
3) Causal inference.
4) #CiCo vs #CIM
5) 1600 lines of R code.
@AJCNutrition with: Mark Pereria, Cara Ebbeling, @LuciaAronica & @davidludwigmd
doi.org/10.1016/j.ajcnâŚ
With many of my favorite things:
1) Open Science.
2)Critical analysis of high quality research.
3) Causal inference.
4) #CiCo vs #CIM
5) 1600 lines of R code.
This is a post-hoc analysis of the DIETFITS, a high-quality RCT from @StanfordMed lead by @GardnerPhD (who kindly reviewed an earlier version of our manuscript) which compared carbohydrate vs fat restriction to achieve weight-loss during one year.
jamanetwork.com/journals/jama/âŚ
jamanetwork.com/journals/jama/âŚ
This trial found non-significant weight-loss differences between both diets.
Additionally, no interaction was observed with genotype nor hyperinsulinemia.
Additionally, no interaction was observed with genotype nor hyperinsulinemia.
1/
Think you can exercise your way to weight loss?
Thank again.
đ§ľ
Think you can exercise your way to weight loss?
Thank again.
đ§ľ
2/
You finish an hour on the treadmill or a sweaty cardio workout, thinking youâve burned off enough for a pizza ârewardâ
Then realize youâve burned 100 calories, at best.
That ârewardâ erases all the hard work & you gain weight
You finish an hour on the treadmill or a sweaty cardio workout, thinking youâve burned off enough for a pizza ârewardâ
Then realize youâve burned 100 calories, at best.
That ârewardâ erases all the hard work & you gain weight
3/
In all the time weâve been following Calories In Calories Out, our collective weight and health have moved in the wrong direction.
#CICO says you can lose weight by exercising into a deficit. But it doesnât make sense.
In all the time weâve been following Calories In Calories Out, our collective weight and health have moved in the wrong direction.
#CICO says you can lose weight by exercising into a deficit. But it doesnât make sense.
A couple years ago, we showed that dietary fructose enhances intestinal tumor growth. Today, Iâm excited to expand these results to the normal intestine and discuss the implications for obesity and cancer. @Nature nature.com/articles/s4158âŚ
Congratulations to @SamwiseT whose tenacity, creativity, and dedication pushed us to the next level. If youâre running a MRT/PTSP be on the lookout for his application next year! @TriIMDPhD @WeillCornellGS
So many gems in here, but letâs start with the big guns. Dietary fructose improves intestinal cell survival and elongates villi. @SamwiseT wrote a semi automated program to quantify the length. Freely available here: github.com/sam-taylor/VilâŚ
1/ Hey #NutritionTwitter -- Help become a resource on #coronavirus/#covid19 and provide good advice and information right now to your followers as this timing is very meaningful.
Whatever partisan battles you've been fighting, I'm sure you originally got in this to help people.
Whatever partisan battles you've been fighting, I'm sure you originally got in this to help people.
2/ Viruses can survive outside the body for a while, but under most conditions it will die in time from exposure to things such as ultraviolet light or heat. This is why quarantining yourself for a couple weeks is so powerful.
You want to isolate it from new hosts (other people)
You want to isolate it from new hosts (other people)
3/ If you have a healthy immune system that is becoming increasingly deadly to the virus inside your body while forcing its remains outside your body (in your living space) to endure exposure before coming into contact with any new hosts, you've massively reduced the risk.
