Discover and read the best of Twitter Threads about #COVID19Vax

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@ChuckCallesto #RussianRonJohnson plagiarizes @GovRonDeSantis who said he would do that. As a Medicinal Chemist who taught drug dev process to Biomedical Scis, MDs,PhDs, PharmDs, I provided a summary. Bottom line #WarpSpeed cut time to market fr 8-15yrs to 2yrs, limiting data #BlameTrump @GOP
@ChuckCallesto @GovRonDeSantis @GOP Drug dev begins w Rational Drug Design of likley candidates, based on Structure Activity Relationship models. Then lab, bench scale prep, efficacy tests, in vitro, then in vivo. Likely candidates tested in rats to get ADME-Tox data.Absorption, Distribution, Metabolism, Excretion
@ChuckCallesto @GovRonDeSantis @GOP 3/ Safety & efficacy tested in animal models (all research animals protected under IACUC protocols under USDA regs). If safe & effective, plans to proceed to Clinical Trials, under @US_FDA guidelines governed by 45 CFR 46 Human Subjects Research protection regs. CT Phases I-IV.
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