Discover and read the best of Twitter Threads about #COVIDOUT
Most recents (1)
The long awaited #COVIDOUT RCT is now in @TheLancet:
- high risk adults randomized to either metformin (MET), ivermectin (IVM), fluvoxamine (FLV) or placebo.
- MET reduced the risk of long COVID (6.3% vs 10.4%; NNT = 24)
- no benefit with IVM or FLV
thelancet.com/journals/lanin…
1/
- high risk adults randomized to either metformin (MET), ivermectin (IVM), fluvoxamine (FLV) or placebo.
- MET reduced the risk of long COVID (6.3% vs 10.4%; NNT = 24)
- no benefit with IVM or FLV
thelancet.com/journals/lanin…
1/
COVID-OUT was a large blinded multicenter RCT looking at repurposed oral meds.
The primary outcome was severe COVID; this was one of the *MANY* negative RCTs of ivermectin. (See 🧵👇)
The current study is a planned secondary analysis, looking at the incidence of long COVID.
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The primary outcome was severe COVID; this was one of the *MANY* negative RCTs of ivermectin. (See 🧵👇)
The current study is a planned secondary analysis, looking at the incidence of long COVID.
2/
COVID-OUT was a factorial design enabling efficient evaluation of multiple oral medications in various combinations.
After diagnosis, subjects received meds by next day mail. They were followed up to 300 days (10 months).
Diagnosis of long COVID was made by a synonym survey
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After diagnosis, subjects received meds by next day mail. They were followed up to 300 days (10 months).
Diagnosis of long COVID was made by a synonym survey
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