Discover and read the best of Twitter Threads about #CRCSM

Most recents (9)

Is there a role for Local Tx of the Primary Tumor for Patients with Metastatic Cancer?

🚫Many studies demonstrate no benefit.
📌We performed a MetaAnalysis to evaluate the average effect of Local Tx across various tumors.

A thread🧵#AMSM #PRIMETX
redjournal.org/article/S0360-…

1/25
Critics of Local Tx to the Primary Tumor

📌 Many providers think local control of the primary tumor in the setting of M1 dz is akin to “closing the barn door after the horse has bolted”
📌 Ian Tannock wrote a fantastic article on this back in 2000.

pubmed.ncbi.nlm.nih.gov/11759650/

2/
Supporters of Local Tx

📌Some support aggressive ablation of all sites due to the enhanced ability to detect occult disease with improved imaging technologies and 📉 toxicities with complete ablation.

pubmed.ncbi.nlm.nih.gov/35831494/
pubmed.ncbi.nlm.nih.gov/31182289/
pubmed.ncbi.nlm.nih.gov/34742582/

3/
Read 28 tweets
TROLLEYS & ONCOLOGY

Every Ethics 101 student wrestles with the trolley problem.

In this exercise, you are placed by train tracks watching a runaway trolley race towards 5 people who are going to be crushed unless you intercede.

THREAD/
If you pull a lever, the trolley will divert on a different track, where it is bound to kill one person.

In this situation, is it better to be passive or active?

Should you pull the lever or not?

2/
While not quite as dramatic a scenario, a similarly freighted decision between inaction and intervention plays out in oncology clinics multiple times every day as doctors weigh the risks & benefits of adjuvant chemotherapy.

3/
Read 12 tweets
Yesterday at #TargetedChat we talked about a challenging case of a young individual with recurrent UNRESECTABLE colon cancer after adjuvant.

Here’s a 🧵 on the questions/answers. No one right away. What would you do differently?👇🏾Read/reply along #ColorectalCancerAwarenessMonth Image
It was interesting to see the distribution on the chemo backbone options.

TRIPLETS 🆚 DOUBLETS #TargetedChat #CRCSM Image
👇🏾With the doublets and triplets discussion, a little bit of art 🖼 to the science 🧪

Have to see and individualize in each patient which tools 🛠 from the toolbox 🧰.

#TargetedChat #CRCSM #ColorectalCancer #ColorectalCancerAwarenessMonth Image
Read 9 tweets
Welcome to #TumorBoardTuesday
Hello Everyone,

I’m Manju George, a stage 3b rectal cancer survivor
I was diagnosed in 2017 & I wasn’t yet 45 then

Are you excited to discuss #CtDNA testing?

Let's get started..
But first things 1st
Tell us about you
#PatientExperience #CRCSM
My tumor
-In the upper rectum near the recto-sigmoid
Clean CAP CT scan & MRI pelvis
CEA 1.0 at dx
LAR sx 1st
Stage 3b rectal, MSS, BRAF WT

No chemo-RT
4 cycles of CAPOX
Clean scans at the end of treatment🎉🎉

What about you?

#TumorBoardTuesday #CRCSM #CtDNA #LiquidBiopsies
Survivorship--Different parts, very nice diagram from @CancerSurvSM
Great patient worksheet resource here--smhs.gwu.edu/cancercontrolt…
#TumorBoardTuesday #PatientExperience #CtDNA
Read 10 tweets
#TumorBoardTuesday
Thursday Case Wrap Up🎀
(Case from 02/02/21)

➡️In case you missed the fast moving conversation, follow this thread for our summary

➡️And also take a look at these Twitter Moments from the case!

Page 1
twitter.com/i/events/13501…

Page 2
twitter.com/i/events/13573…
👏What a great #TumorBoardTuesday discussion on MSI-high, and NTRK-fusion+ #CRCSM led by @pashtoonkasi

Don't forget the 🏆🆓credit!!
✅2 Post-Test❓ integrityce.com/tbt2-2

⬇️⬇️Here is a breakdown of the participants⬇️⬇️ Image
#TumorBoardTuesday
Thursday Case Wrap Up🎀
(Case from 02/02/21)

We started with 2 pre-case poll questions⬇️ Image
Read 9 tweets
Thank you @BilalMohammadMD @AmyOxentenkoMD for reigniting a convo ab #medtwitter #GITwitter, an important facet of the healthcare #SoMe landscape.

Let's review a few analyses we performed over the years on engagement + impact of GI #SoMe:
(Evidence to convince more to join?)

🧵
Q: Is there benefit to divisional social media presence for a healthcare dept/institution?

With @DrLorenGR @walterchanMD we demonstrated an ⬆️ in institutional social media presence predicted GI divisional #ranking improvement on @USNewsHealth

jmir.org/2019/9/e13345/ @jmirpub
As mentioned, with @BrennanSpiegel @Doctor_V we created the GI hashtag ontology in 2016 to standardize GI discourse on Twitter with all GI societies/journals at the time, after a discussion w @subatomicdoc whose work in Heme/Onc inspired us. @symplur

journals.lww.com/ajg/Citation/2…
Read 15 tweets
Bird’s-eye view 👁 on what to look out for @WCGIC #WorldGI2020.
Opening remarks on important data 📺 @myESMO - by Dr. Eric Van Cutsem @UZLeuven.
🟩Good to see more #PrecisionMedicine🧬
🟥#Immunotherapy #Immuno-#oncology
🟦TNT & other chemo strategies
@Annals_Oncology #OncoAlert
🆕#ctDNA #liquidbiopsies 🩸🧬
👀 👇🏾at the number of #clinicaltrials cropping up in this space‼️
🇦🇺DYNAMIC-II
🇦🇺DYNAMIC-III
🇺🇸COBRA @NRGonc
🇺🇸BESPOKE
🇺🇸@SU2C
🇯🇵 CIRCULATE
🌎COLUMBIA
🇮🇹🇪🇸PEGASYS
🇬🇧TRACC
🇩🇪CIRCULATE
🇫🇷crEATE
🇩🇰IMPROVE-IT
We have 2🇺🇸studies open. #CRCSM #WorldGI2020
#WORLDGI2020 This is 🆒 ☢️ 32-P EUS-guided implantation in #pancreascancer #PANCSM @myESMO @WCGIC @Annals_Oncology.

Still miles to go. OS median of 16 months pointing again to the systemic nature of disease. Need to piggyback these local approaches to better systemic. #OncoAlert
Read 55 tweets
@DrSidMukherjee Wild idea: what about rise of oncology patient advocate (individuals, not orgs) -led communities & activities empowered/fueled by the tools of social media, and their effect on clinician/researcher/pt collaborations/research direction?
cf @GRASPtweets at #sabcs19; @COLONTOWN
@DrSidMukherjee @GRASPtweets @COLONTOWN In 1994 at my 1st dx was given H. Benjamin’s “From Victim to Victor” mentioning concept of active patient. Fast fwd thru 2nd & 3rd dxs and I find myself part of the #ePatient mvt. Discover power of twitter hashtags to unite equal multi-stakeholders in convos that (still) lead...
@DrSidMukherjee @GRASPtweets @COLONTOWN ... to collaborations, be they via #bcsm (@GRASPtweets @MBC_Project) #lcsm (@ros1cancer @EGFRResisters), #btsm, #gyncsm, #crcsm, etc. Individual advocates collaborating as equals with cancer scientists & clinicians, giving TRUE meaning to the “pt-centered” buzzword.
Read 7 tweets

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