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Ok morning meetings done! I will kick off today by talking a little bit about how I ended up all the way in Sweden.
I originally did my undergraduate studies within at @Sydney_Uni. I was actually originally studying a combined science, commerce degree at the time!
I originally did my undergraduate studies within at @Sydney_Uni. I was actually originally studying a combined science, commerce degree at the time!
However, in my third year I rediscovered my love for crystals and discovered the joys of #crystallography in the solid state chemistry course. This led to a research project in @SydneyChemistry in 2009 on lithium conduction in defect perovskites that grew into my PhD project. 
I will talk more on the science of my project later. For now how did I find my way to Sweden? Well, I was fortunate enough in my PhD to have to opportunity to travel abroad to conferences. Such as AsCA in Busan Korea (where I looked very different compared to today...)
🌄Good evening everyone!
Welcome to In Conversation with 𝐃𝐫 𝐑 𝐂𝐡𝐢𝐝𝐚𝐦𝐛𝐚𝐫𝐚𝐦, Former Principal Scientific Adviser to Govt. of India, Chairman AEC & Secretary @DAEIndia👥
🗣️Please post your recommendations, comments with #ChatwithRChidambaram
Welcome to In Conversation with 𝐃𝐫 𝐑 𝐂𝐡𝐢𝐝𝐚𝐦𝐛𝐚𝐫𝐚𝐦, Former Principal Scientific Adviser to Govt. of India, Chairman AEC & Secretary @DAEIndia👥
🗣️Please post your recommendations, comments with #ChatwithRChidambaram
1/ It's been a very busy few weeks in the Walsh group @diamondLightSou but extremely happy to announce that in collaboration with Frank von Delft group’s at Diamond we have been able to perform a full X-ray fragment based drug discovery experiment on the SARS-CoV-2 main protease
2/ We have released all data from this work here: diamond.ac.uk/covid-19/for-s… #covid19 #SARS_COV_2 #DrugDiscovery #AntiviralDrugs #structuralbiology #crystallography #cryoEM #nmr We will update data as its generated to accelerate drug development to combat #COVID19 @JeremyFarrar
3/ This has been an amazing team effort involving on the science side my group (Petra Lukacik, Claire Strain-Damerell & David Owen) and Frank von Delft's XChem Team (Primarily Alice Douangamath, Daren Fearon) and Ailsa Powell from the @DiamondILO @EJShotton team
cGAS-STING work continues to boggle the mind - flurry of new papers in the last two weeks branching the field in new directions. I’ll try for quick (not really) takes… #cGAS #microbiology #Immunology #Inflammation @nature @biorxivpreprint @NatureMicrobiol @CellReports
Paper 1: @aaronwhiteley et al writing in @nature - nature.com/articles/s4158…. cGAS-like nucleotidyltransferases in bacteria (CD-NTases) synthesize a wide range of cyclic dinucleotides (CDNs) - and more, including trinucleotides (CTNs?)!
Different CDNs and CTNs activate different host sensors - for example, many that don’t activate STING instead activate RECON. Dozens of CD-NTases are shown to synthesize a wide range of products, including CTNs - which can also activate RECON.
After a jam-packed 2 days at #SciOut18🌪(thx @ASBMB & @rockedu_!) it was time to reflect! 🤔 Reflection is so important, but it can be hard to find ⏰ to really just think! 💭 Some of my thoughts 👉 instagram.com/p/BokNO_NhihF/
#365DaysOfScience #biochemistry #scicomm #sciout #science
#365DaysOfScience #biochemistry #scicomm #sciout #science
What’s inside? 🧐 It’s FORMAMIDE! 🤗 Formally removing RNA’s form with formamide! 🤓 FORMAMIDE in loading buffer breaks up & replaces the bonds between bases holding RNA's shape together 👇
instagram.com/p/BomwR32B4MX/
#365DaysOfScience #biochemistry #scicomm #lifeinthelab #science
instagram.com/p/BomwR32B4MX/
#365DaysOfScience #biochemistry #scicomm #lifeinthelab #science
Bring on the heat! 🔥 To help denaturants get to the huddling hydrophobic bases, we add heat ♨️ 👉 gives molecules more energy so they can “pull apart” more easily ⏩ easier access 👍 More 👇
instagram.com/p/Boo2yazBDDi/
#365DaysOfScience #biochemistry #scicomm #lifeinthelab #science
instagram.com/p/Boo2yazBDDi/
#365DaysOfScience #biochemistry #scicomm #lifeinthelab #science
