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Really excited that my first first-author paper (with @AtomicVirology) has been submitted and is available as a preprint on BioRxiv! Check it out: biorxiv.org/content/10.110…
#phdlife #AcademicChatter
I'll summarise the main findings in this thread (1/8)
@AtomicVirology The paper focuses on pUL7 and pUL51, conserved proteins from herpes simplex virus (HSV)-1 that form a complex required for efficient virus assembly. We used small-angle X-ray scattering with @svergungroup @embl Hamburg to characterise the complex in solution. (2/8)
@AtomicVirology @svergungroup @embl We used X-ray crystallography to solve the atomic-resolution structure of the core pUL7:pUL51 heterodimer. pUL7 forms a single, compact, globular domain that is bound to pUL51, which forms an extended helix-turn-helix, via an extensive hydrophobic interface. (3/8)
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