Discover and read the best of Twitter Threads about #Cardiovascular

Most recents (24)

1) Welcome to a 🆕accredited tweetorial from @cardiomet_CE! We welcome back expert faculty @ChristosArgyrop to discuss screening for #CKD in pts w/ #T2D & the role of routine assessment for #microalbuminuria as an effective diagnostic, risk stratification, & patient ed tool.
2) Christos Argyropoulos MD, PhD @ChristosArgyrop is Division Chief, Nephrology @UNMHSC. #CKD is chronic #kidneydisease, #ESKD is end-stage kidney disease.
#FOAMed #nephtwitter #cardiotwitter @MedTweetorials @NephUCommunity @ISNkidneycare @KidneyDiseaseFm Image
3) This program is intended for #HCPs and is supported by an unrestricted educational grant from Bayer. Statement of accreditation & faculty disclosures at cardiometabolic-ce.com/disclosures/.
FOLLOW US for more expert-authored #tweetorials and earn #MedEd
Read 43 tweets
2/
Classically placed in the arm
May be placed in the leg (eg in #pediatrics /neonates – which may then terminate in the infrarenal IVC/iliacs)
.
#criticalcare #cardiovascular
3/
Advantages:
- Lower infection rate then central lines
- Used in the outpatient setting
- Can be used for several weeks to months
- Duration of PICC lines may be from 4 weeks to 6 months
(although they have been known to be functional for more than 300 days)
Read 20 tweets
Avec des vaccins à l'efficacité de plus en plus limitée (50% au mieux face à XBB 1.5 contre plus de 90% sur les premiers variants)
francais.medscape.com/voirarticle/36…

> face à l'échappement immunitaire, quelle logique de l'obligation vaccinale si d'ici l'été la protection tombe à 25/30% ?
On peut aussi noter le variant BQ.1.1 Cerberus...

À chaque mutation de + en + sélectionnée par la pression immunitaire et vaccinale, le virus mutant résistant est sélectionné et diminue l'efficacité vaccinale car la vitesse d'évolution et complexité du virus va + vite ImageImageImage
De + chaque réinfection ⬆️ les risques de décès, d'hospitalisation, mais aussi de + en + kde séquelles, notamment pulmonaires, troubles cardiovasculaires, hématologiques, diabétiques, gastro-intestinaux, rénaux, de santé mentale, musculo-squelettiques et neurologiques.
Read 14 tweets
1/As promised & after reading $CRSP latest Q4 2022 #financial #report here is my impression regarding @CRISPRTX latest corporate status. I have focused only on the main issues that I found to be the most interesting & relevant. #CRISPR #BioTech #FinTwit #Genomics #GeneEditing 🧵 CRISPR Therapeutics, a biopharmaceutical company focused on
2/IMO the most significant corporate event in Q4 was $CRSP announcement that regulatory Exa-cel submissions of both #SickleCell & #BetaThalassemia validated in the #EU & #UK & that the @US_FDA BLA submission is on track by the end of Q1 ‘23 - possibly reaching the #markets in ‘23 Regulatory submissions complete for exagamglogene autotemcel
3/Exa-cel/CTX001 - the key program in $CRSP portfolio, is an #autologous Ex-Vivo #CRISPR/#Cas9 #GeneEditing therapy aimed for patients suffering from #TDT or severe #SCD. The latest readout for both programs was phenomenal with 42/44 TDT & 31/31(!) demonstrated remarkable results 3/Exa-cel - formally known as CTX001 and the key program in
Read 17 tweets
Its not so #cool as it sounds... because of the following,

#Eating #redmeat has been associated with various #health problems, including:
#Cardiovascular disease: High consumption of red meat has been linked to an increased risk of #heart disease due to

1/n
the high levels of saturated fat and #cholesterol found in red meat.
#Cancer: Several studies have suggested that high consumption of red meat, particularly processed #meat, can increase the risk of certain cancers, such as colon cancer.
2/n
Type 2 #diabetes: Red meat consumption has been linked to an increased risk of developing type 2 diabetes, potentially due to the high fat content.
#Obesity: High consumption of red meat has been linked to an increased risk of obesity due to its high #calorie and fat content.
3/n
Read 7 tweets
1/2 "#COVID-19 infection, including long-COVID, is associated with increased short- and long-term risks of #CVD and mortality."

#cardiovascular #disease #health #COVID19 #SARSCoV2
2/2 "Ongoing monitoring of #signs and #symptoms of developing these #cardiovascular #complications #post #diagnosis and up till at least a year post recovery may benefit infected patients, especially those with #severe #disease."

#PASC #LongCovid
1/2 "Compared to #uninfected individuals, the likelihood of #COVID-19 patients dying was up to 81 times higher in the first three weeks of infection and remained five times higher up to 18 months later."

#SARSCoV2 #COVID19 #cardiovascularhealth
Read 4 tweets
Sehr aktueller Preprint zu #longcovid und #Genalayse und #GProteinGekoppelteRezeptoren

Kurze Zusammenfassung / Short summary of this data analysis

Long COVID: G Protein-Coupled Receptors (GPCRs) responsible for persistent post-COVID symptoms biorxiv.org/content/10.110…
Durch computergestützte Methoden wurden 255 #LongCOVID-#Symptome analysiert und die dazu relevanten Gene identifiziert.

This work utilised computational methods to analyse the persistence of COVID symptoms after recovery and to identify the relevant genes.
Protein-protein interaction network overview. Nodes = proteins, edges represent the interaction between two nodes (proteins). The top 10 key hub #genes of 255 symptoms of #longcovid are related to G-protein coupled receptors shown in circular nodes in pink.
Read 11 tweets
The less we eat, the longer we live

1. This seems to be true.
A recent extensive review of studies done in geographies with maximum 100+ aged people showed that most of them practiced some form of calories restriction (CR) right from childhood.
#fasting #Longevity #MedTwitter
2. Calorie restriction (CR) is defined as consuming fewer (10-30% lower) calories as compared to usual.
This can be achieved by either intermittent fasting, or time-restricted feeding or substantially reducing carbohydrate intake.
#nutrition #HealthyEating
3. In ageing, #Insulin increases and insulin sensitivity decreases, which increase the risk of #diabetes, #obesity and #cardiovascular diseases. CR reverses these- reduces insulin levels and increases insulin sensitivity. #Glucose levels also reduce with CR.
Read 10 tweets
1/🚨New Episode🚨
The Lipid Panel Reimagined: #MindtheGap Segment

How do you interpret the #lipidpanel to help inform patients' risk for #cardiovascular disease? Do you use #ApoB? 🧐

🎧: link.chtbl.com/Lipids
Sponsor: go.amboss.com/CoreIM-E8
2/ Unfortunately, our patient is stuck in "bumper-to-bumper" #cholesterol traffic 🚗!

See traffic analogy to understand why ApoB can give us information that LDL-C may not:

#Mindblown! 🤯
3/ Overall, LOWER ⬇️ is better for both #LDL-C and #ApoB in terms of reducing #CV disease risk!

But #discordance between LDL-C vs. ApoB is actually quite common!

Take a look at the orange line to see how ApoB confers a higher CVD risk over time 👇
Read 5 tweets
White coat #hypertension (WCH) can not be left alone

1. Patient: My BP is high only in hospital, at home it is normal. So, I don't want to do anything about it.
Me: High BP (whether in hospital or at home) can lead to adverse outcomes, so, you should aim for a normal BP 24/7.
2. A study showed that in untreated cohorts, WCH was associated with a 38% and 20% increased risk of #Cardiovascular disease (CVD) and total #mortality (death) compared with normotension (normal BP), respectively.
3. However, in the treated patients (who received medications to keep BP normal at office as well as at home), neither the risk of CVD, nor total mortality was increased in WCH.
Read 5 tweets
1a) Welcome to a new #accredited #tweetorial on the management of aFXa-DOAC-associated #hemorrhage and specifically the role of coag laboratory testing in these challenging cases.
1b) Our expert author is #pharmacist Craig Beavers, PharmD @beaverspharmd CV Clinical Pharmacy Specialist @UK_COP, and Immediate Past Chair of the @ACCinTouch #ACCCVT Section
2) This 🆓program is accredited for 0.5h CE/#CME for #physicians #physicianassociates #nurses #nurespractitioners #pharmacists and is supported by a grant from AstraZeneca. See statement of accreditation and faculty disclosures at cardiometabolic-ce.com/disclosures/.
Read 37 tweets
Empagliflozin is now my go-to SGLT2i for pts with #diabetes and #CKD or #CHF, over cana or dapa or ertu.

Why?

A: EMPA-KIDNEY: nejm.org/doi/full/10.10…
and EMPEROR-Reduced and EMPEROR-Preserved
1/
EMPA-KIDNEY is unique because it enrolled GFR 20-45 *without* proteinuria whereas others (DAPA CKD, CANVAS) enrolled pts with CKD+proteinuria, though DAPA-CKD conducted a subgroup analysis for UACR < and > 1000
The primary outcome was a composite of progression of #kidney disease (defined as #ESRD, a sustained decrease in eGFR to <10, a sustained decrease in eGFR of ≥40% from baseline, or death
from #renal causes) or death from #cardiovascular causes
Read 7 tweets
Nyt sitä saa. #Oulu #Kiuru-#Marin-#provisio-#piikittää kaikki, poliittisella päätöksellä.
- Ikää, lääkärilupia, #InformedConsent eikä myyntilupien perään kysellä.
- Virkavallalla on muuta kiireitä, #moporatsia't ja muutakin on.
- #Fimea ja @ValviraSoteValv vaiennettu.
@ValviraSoteValv Vietä ihana #Pharmageddon-#Joulu2022
#Oulu sai juuri lisää #krematorio -kapasiteettia, ei tarvitse röykkiöissä, lojua
#Joulu2022 koteihin ei tulekaan #Joulupukki -#Ivermectin -pakettien kaa, lapsiperheistä lähtee moni iskä ja äippä aikaisin #TaivaanKotiin
Read 6 tweets
1/🚨New Episode🚨
Aspirin for Primary Prevention: #MindtheGap Segment

What do current ACC and USPSTF guidelines say about daily low-dose #aspirin for the primary prevention of #cardiovascular disease?

🎧: apple.co/3VPRCV4
Sponsor: bit.ly/TCChoZ Image
2/Throwback to medical school pathophysiology!

Remember how the #atherosclerotic process takes place in blood vessels? 🫀

Now, where does #aspirin exert its effect during this cascade? 🤔 Image
3/What do the most recent #RCTs inform us about the use of aspirin for primary prevention ⁉️

ASCEND, ARRIVE, ASPREE!

#CoreIMJournalClub 📕 Image
Read 6 tweets
1) Welcome to a new #accredited (0.75h CE/#CME) #tweetorial on challenging case presentations for pts with #cardiometabolic disease, #CaReMe #FOAMed.
Our expert author is Claire Davies. @claireyrivs is a specialist diabetes & endocrinology #pharmacist working in Gateshead in 🇬🇧. Image
2) She is a member of UKCPA Diabetes & Endocrinology committee @UKCPADiabetes & works across #diabetes, #endocrinology, & emergency/acute care in Secondary Care. She is currently involved in development of regional guidelines & education to support medicines optimisation for PLWD
3a) This program is intended for healthcare professionals and is supported by an educational grant from Boehringer Ingelheim Pharmaceuticals Inc. and Eli Lilly Company.
Read 36 tweets
Please retweet and share if you support my and others' vaccine injury recoveries. Image
My fiancé and I were supposed to get married in July 2022. Given the first 2 vaccine mandates, we figured that we had no choice but to keep on taking the boosters in order to be able to travel for our honeymoon / have liberties to go to stores etc.
We decided to take the 3rd @moderna_tx booster anticipating that perhaps it would also be mandated by the #Canadian #government.
Read 76 tweets
ACC & @American_Heart released a 🆕report outlining key data elements & definitions for #ChestPain & acute myocardial infarction (#MI) based on the 2021 ACC/AHA Chest Pain Guideline. Take🏠Points in🧵Below ⬇️ #cvAMI #ClinicalGuidelines #JACC @JACCJournals
@American_Heart @JACCJournals 1⃣ The #ACCClinicalDoc presents a clinical lexicon of data elements related to #ChestPain & #cvAMI, in context of how the terms are used in the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR #ClinicalGuideline for the Evaluation and Diagnosis of Chest Pain: bit.ly/3CIBldf
2⃣ This lexicon follows the plans contained in the new #chestpain guideline and NOT all conceivable types and causes of chest pain are considered here. #ClinicalGuidelines @JACCJournals Image
Read 12 tweets
1) Welcome to our new #accredited #tweetorial which is Part 2 of a 2-part "highlights" program on new #SGLT2i & #DKD data presented at @ERAkidney #ERA22. #Physicians #nurses #pharmacists #PAs and #NPs can all earn 0.5h CE/#CME by following this 🧵!
2a) @ERAkidney #ERA22 is a primary international scientific symposium for interaction and exchange among basic scientists and clinicians working in #Nephrology. Our expert author is Dr. Clara García Carro (@ClaraGCarro) from San Carlos Clinical Hospital (Madrid, Spain).
2b) Be sure to check out the first half of this #ERA22 recap from my colleague @shbermejo, and get MORE 🆓CE/#CME at ckd-ce.com/dkd12_ERA22a/. Join me in following @ckd_ce for the BEST in #cardiorenal education delivered entirely by #tweetorial!
Read 48 tweets
1) Welcome to our new #accredited #tweetorial which is Part 1 of a 2-part "highlights" program on new #SGLT2i & #DKD data presented at @ERAkidney #ERA22. #Physicians #nurses #pharmacists #PAs and #NPs can all earn 0.5h CE/#CME by following this thread!
2) @ERAkidney #ERA22 is a primary international scientific symposium for interaction and exchange among basic scientists and clinicians working in #Nephrology. It was held in May. Our expert author is Dr. Sheila Bermejo (@shbermejo) from @vallhebron in Barcelona, Spain.
3) This program is #accredited for CE/#CME & is supported by an independent educational grant from the Boehringer Ingelheim/Lilly Alliance. It is not intended for US- or UK-based based HCPs. Accreditation statement & faculty disclosures at ckd-ce.com/disclosures/.
Read 43 tweets
1) Welcome to a new #accredited #tweetorial on optimizing the role of the pharmacist in managing cardiometabolic disease! Accredited for 0.50 hr for #physicians #nurses #pharmacists! Expert faculty is Snehal Bhatt PharmD @SnayCardsPharmD of @BIDMChealth. Image
2a) This educational activity is supported by grants from Bayer, Otsuka, & Boehringer Ingelheim Pharmaceuticals Inc. and Eli Lilly Company. See archived programs, all by expert authors, still available for credit at ckd-ce.com.
2b) Accreditation statement and faculty disclosures are at ckd-ce.com/disclosures/. We are your ONLY source for accredited education in CKD and #cardiorenal disease delivered wholly on Twitter. FOLLOW US!
Read 24 tweets
Now we'll talk #polyphenols and #PrecisionNutrition in this next science packed session at #Nutrition2022. #NutritionLiveOnline Image
Oh look the #microbiome is here too! 🥰👏🥳 Yes, polyphenols are key to the #GutMicrobiome. Let's learn more.
#Nutrition2022 #NutritionLiveOnline Image
But first the #metabolome and polyphenols. #Nutrition2022 #NutritionLiveOnline Image
Read 12 tweets
The 2022 Atwater Lecture, "#Nutrition Misinformation: Who's Right? Who Gets to Decide," is from Alice Lichtenstein, DSc, a fatty acid expert and researcher working in #cardiovascular disease, including uncovering the dangers of trans fat. #Nutrition2022 #NutritionLiveOnline Image
What's the purpose of #nutrition information? This one, we all seem to agree on...
#Nutrition2022 #NutritionLiveOnline Image
Despite three recent updates to the Dietary Guidelines for Americans, #diet quality has not improved. We're not moving the needle for the average American. #Nutrition2022 #NutritionLiveOnline Image
Read 11 tweets
1) Welcome to an #accredited #tweetorial on optimizing the use of #SGLT2i in the management of #T2D. This program is accredited for 0.50 🆓credits for #physicians #nurses #physicianassociates #nursepratcitioners #pharmacists by @academiccme! I am @tmodarressi of @HeartDoctorNJ.
2) This program is intended for healthcare professionals and is supported by an educational grant from Boehringer Ingelheim Pharmaceuticals Inc. and Eli Lilly Company. See archived programs, all by expert authors, still available for credit at cardiometabolic-ce.com.
Read 47 tweets

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