Discover and read the best of Twitter Threads about #Cell_Therapies
Most recents (3)
1/ This has been a huge love of mine for years. The engineering of cells to create cancer therapies. The induced Pluripotent Stem Cells (iPSC) can revolutionize the way we create CAR-T or CAR-NK cells for cancer treatments.
2/ The process of the iPSC can be automated, duplicated and consistent as a source of low cost cell therapies. So how does this work?
1/ NK cells are a close cousin to the cytotoxic T cell so it is only logical that scientists would look at them for use in cell therapies to treat cancer. They use the same cytotoxic mechanisms to kill infected or defective cells.
2/ There are some major difference between the CD8+ T cells and the NK cell. The first is the NK cell does not use MHC I the same as the T cell. The cytotoxic T cell reads the MHC I on the cell along with any antigens it is presenting. It works with the MHC I.
