Discover and read the best of Twitter Threads about #Chemotherapies

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Scientists at @bbglab at @IRBBarcelona have determined for the first time the genetic alterations in the cells of cancer patients that are caused by the main therapies used to treat this disease.👇Read this thread about this study published in @NatureGenet
irbbarcelona.org/en/news/geneti… Image
#Chemotherapies have transformed the treatment of #cancer, allowing the survival of many patients. Some of these therapies kill cancer cells by damaging their DNA🧬. However, these drugs can also harm the healthy cells and produce long-term side effects.
As a first step towards understanding the relationship between these mutations and the side effects of #chemotherapies, the @bbglab studied the sequence of the metastatic tumours of around 3,500 patients😯and identified a specific pattern of mutations: the “mutational footprint”.
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