Discover and read the best of Twitter Threads about #CoMMpass

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Trying something new today - a thread on high-risk #multiplemyeloma.

I’ll focus this thread on clinical factors and will try to dive into cytogenetics/molecular biology at a later time.

This is my first "tweetorial", so any input/advice/commentary is welcome! #mmsm
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2/ How is high-risk #myeloma (HRMM) defined and why does it matter?

Most pts with #HRMM respond well to initial tx, but it is often challenging to maintain disease control. Once PD occurs, HRMM is very difficult to treat.

This has potentially important management implications.
3/ The most widely used tool for risk stratification in MM today is the Revised International Staging System (R-ISS) tinyurl.com/yxjzpk5p. Pts are stratified into one of 3 “stages” based on 4 factors:

1. Albumin
2. Beta-2-microglobulin (B2M)
3. LDH
4. Cytogenetics
Read 15 tweets

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