Discover and read the best of Twitter Threads about #ComplexDisease
Most recents (2)
OK, looks like Democracy is safe for now, and the push for reform is making headway. There's a long road ahead, but I'll take a brief timeout to report from @NYASciences's #Phenotypic2020 virtual conference.
First keynote was @OlgaTroyanskaya, presenting a range of tools for understanding #NonCoding genomic variants: DeepSEA, ExPecto, Fenrir...
Emphasizes that #ComplexDisease relies on networks and complex changes like #Aging, so we have to stop looking for 1->1 causal maps. Agree!
Emphasizes that #ComplexDisease relies on networks and complex changes like #Aging, so we have to stop looking for 1->1 causal maps. Agree!
Andrea Califano from @columbiacancer using combination of #HTS and #SingleCell Plate-Seq to look for cancer master regulators. VIPER identifies proteins whose regulatory effect impacts genes that distinguish cell states. Now running phase 1 trial!
Gordian is speaking at the (virtual) #asgct2020. Come hear how we do entire #HighThroughput #GeneTherapy screens for #ComplexDisease, all in a single animals. We'll show large animal data, and some basic #AAV biology we learned along the way. Tuesday 13:45 EST, Room 312. 
There's some tough competition in the #ASGCT20 program today, especially from the juicy #AAV vector biology session.
But if you're curious about how #GeneTherapy can be extended to non-monogenic diseases, I think we've got the Tuesday afternoon market cornered!
But if you're curious about how #GeneTherapy can be extended to non-monogenic diseases, I think we've got the Tuesday afternoon market cornered!
Coming up in 10 minutes! in session "Aav vectors preclinical and proof of concept studies in optimizing the toolbox". #ASGCT20
