Discover and read the best of Twitter Threads about #CovidToes
Most recents (11)
Cutaneous Reactions Reported after #Moderna and #Pfizer COVID-19 Vaccination - our study on 414 cases out in @JAAD today. Many different rashes after vaccination, not just of arm. @KimberlyBlumen1 @MishaRosenbach @juleslipoff jaad.org/article/S0190-… 🧵
#dermtwitter #medtwitter
#dermtwitter #medtwitter
Ready for the good news? Less than 50% of patients with cutaneous reactions after the first dose experienced second dose recurrence. None reported serious adverse events. #dermtwitter #MedTwitter
The most common morphologies were delayed large local reactions, local injection site reactions, urticaria, and morbilliform eruptions. jaad.org/article/S0190-…
Anniversary of me taking this pic of my kid’s food and sending it to my medical friends “what the hell is this?”
In another few weeks it would look like this, and the second kid came to me with similar but milder toe findings, and we all figured out we’d probably had COVID about 8 weeks after the fact. 🤷🏻♀️ #covidtoes
Subsequent derm papers showed actual virus particles in the small vessels in the feet of similar patients, also patterns of type 1 interferonopathy vasculitis.
There is an intriguing theory about “COVID toes.” You can get it as a result of SARS-CoV-2 infecting you.
But you can also – perhaps – get it *without* being infected, as a result of hanging out at home for long periods without shoes. It's an epidemiological puzzle. 1/
But you can also – perhaps – get it *without* being infected, as a result of hanging out at home for long periods without shoes. It's an epidemiological puzzle. 1/
COVID toes are thought to be a known, albeit formerly rare, condition called chilblains (also known as pernio). This used to be the bane of people living in cold damp climates (think British boarding schools, or New England). #COVIDtoes 2/
Chilblains is characterized by inflammatory skin lesions in patients exposed to non-freezing weather during late winter or early spring. These lesions typically present as painful erythrocyanotic (red-blue) discoloration, often with dead skin, on the toes, fingers, or both. 3/
#PresidentialDebates should not happen without #LiveFactChecking, especially when our #despot is infamous for lies! This is a thread which attempts to dispute some of #TheHateYam's lies. The #SecondPresidentialDebate2020 begins at 24:19 on this video.
At 28:00 #PresidentDeathBreath congratulates himself on what he's done in terms of #PPE. All he did was loot the #FederalStockpile they sold it at auction abroad for #TrumpCrimeSyndicate profit, then #Kushner said it was their own not #ThePeoplesStockpile! abcnews.go.com/Politics/kushn…
Then he replaced the quality, American made #PPE stolen from #ThePeoplesStockpile w/substandard mice chewed expired crap he bought from #Putin, he allowed #Putin to fly it into #Boston on fighter jet! #Russian fighter jets do not belong in our airspace! politico.eu/article/corona…
Really interesting (follows up on the case of two sets of brothers with severe COVID-19) sciencemag.org/news/2020/09/h…
We produce interferons in response to infections. These interferons “interfere” with viral replication. Coronaviruses have some protection against this because they have a replication checking enzyme (this is why coronaviruses mutate more slowly than some other viruses like flu)
Interferon is also used as an anti-viral agent (used to be a treatment for HIV and Hep C)
1/n Continuing the discussion of the #bradykinin hypothesis, from the old thread ()
2/n You'll have to be a real multiplex cycle geek to like the next couple of tweets, but I'll get back to keeping it simple after those next tweets.
From Figure 2 of the paper, elifesciences.org/articles/59177, when the renin–angiotensin system (RAS) system goes wonky, it gets complex
From Figure 2 of the paper, elifesciences.org/articles/59177, when the renin–angiotensin system (RAS) system goes wonky, it gets complex
3/n Click on the pix to enlarge; read the paper. The aim of these overly geeky tweets is to be able to explain soon the important bits simply. The below is just an aid to understanding the above.
(1/12) The #CovidToes mystery deepens again.
It looks like they are caused by #SARSCoV2 after all, but people have been looking with the wrong test.
It seems pretty conclusive now that #COVID19 cases in children are being missed.
A short thread...
It looks like they are caused by #SARSCoV2 after all, but people have been looking with the wrong test.
It seems pretty conclusive now that #COVID19 cases in children are being missed.
A short thread...
(2/12) First, the paper which started it all.
Doctors in Italy noticed "an epidemic of acroischemic lesions of some toes and fingers in asymptomatic children and adolescents", at the height of the epidemic but weren’t able to do testing.
Doctors in Italy noticed "an epidemic of acroischemic lesions of some toes and fingers in asymptomatic children and adolescents", at the height of the epidemic but weren’t able to do testing.
(3/12) Subsequent research found that at least some children with #CovidToes test positive (by RT-PCR) for #SARSCoV2.
This suggested that the phenomenon might be a way to spot some of the children who might be asymptomatic carriers.
This suggested that the phenomenon might be a way to spot some of the children who might be asymptomatic carriers.
The weekly clinical update on TWiV is out today. Always feel like I need to be taking notes (first 30-40 min) podcasts.apple.com/us/podcast/thi…
Daniel noted a paper “the landscape of cognitive function in recovered covid patients...severity relates to elevated CRP. ncbi.nlm.nih.gov/pmc/articles/P…
#toevid and telogen effluvium came up again just in case you missed me freaking out live on twitter because we diagnosed ourselves with COVID two months after we were actually sick...I recapped the story recently https://t.co/Ib09djSK9w
All right #dermtwitter & #medtwitter, it's time for the...
@MedDermSoc & @DermHospitalist Mini-Symposium on #COVID19 & #dermatology!!
I will be attempting to #livetweet the Zoom meeting!
Join along if you'd like. I will be using the h/t #COVIDDerm!
@RoxanaDaneshjou @dschless
@MedDermSoc & @DermHospitalist Mini-Symposium on #COVID19 & #dermatology!!
I will be attempting to #livetweet the Zoom meeting!
Join along if you'd like. I will be using the h/t #COVIDDerm!
@RoxanaDaneshjou @dschless
Let's get started!!!!
Your cohosts are super excited to have you join. To give a little background, this meeting was planned in ~1 week, and we have over 500 RSVPs!
@MishaRosenbach now kicking us off with #COVIDDerm!
Your cohosts are super excited to have you join. To give a little background, this meeting was planned in ~1 week, and we have over 500 RSVPs!
@MishaRosenbach now kicking us off with #COVIDDerm!
.@DrEstherFreeman is speaking and reminding us all to register our #COVID19 #dermatology cases in the @AADskin #COVID registry!
Reminder to do so here:
aad.org/covidregistry
#COVIDDerm
Reminder to do so here:
aad.org/covidregistry
#COVIDDerm
It is an enormous pleasure to be part of this #paper: #COVID-PIEL, the Spanish muticentric study of the #cutaneous manifestation of #COVID19 has just been published in the prestigious journal British Journal of Dermatology! 375 patients included! Conclusions here 👇 (#thread)
A new classification of #skin manifestations of #COVID19 is proposed: 1. Acral areas of erythema-oedema with some vesicles or pustules (19%); 2. Other vesicular eruptions (9%); 3 Urticarial lesions (19%); 4. Other maculopapules (47%) and 5. Livedo or necrosis (6%)
1⃣ Acral lesions, #COVIDtoes, pseudo-chiblains..., affected young patients and lasted a mean of 12,7 days to appear in the course of COVID. They were associated with less severe disease. Itchy (30%) or painful (32%).
1/
Okay #medtwitter and #dermtwitter, you knew it was only a matter of time, didn’t you?! Let’s do this #COVID19 themed #medthread:
#COVID TOES, a #TWEETORIAL!
#MedEd #FOAMEd #dermatology #dermatologia @AADskin @AADMember @Meddermsoc @dermhospitalist
Okay #medtwitter and #dermtwitter, you knew it was only a matter of time, didn’t you?! Let’s do this #COVID19 themed #medthread:
#COVID TOES, a #TWEETORIAL!
#MedEd #FOAMEd #dermatology #dermatologia @AADskin @AADMember @Meddermsoc @dermhospitalist
2/
First, a word of caution – this is one person’s thoughts on a new skin finding reported in a new disease that the medical community is still learning about! As such, nothing in the #tweetorial should be regarded as definite. Just wanted to share a thought process!
First, a word of caution – this is one person’s thoughts on a new skin finding reported in a new disease that the medical community is still learning about! As such, nothing in the #tweetorial should be regarded as definite. Just wanted to share a thought process!
3/
So, who cares? #COVID19 is devastating, at times even for the young & healthy! But it’s all respiratory, right?
Well, as we're learning, there's so much more to #SARScov2, and as a #dermatologist, this is the perfect example of how the exam helps frame possible mechanisms.
So, who cares? #COVID19 is devastating, at times even for the young & healthy! But it’s all respiratory, right?
Well, as we're learning, there's so much more to #SARScov2, and as a #dermatologist, this is the perfect example of how the exam helps frame possible mechanisms.
