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Let's talk about YEAST!
🤔What are they
🤒Which ones cause human disease
🧫How do we ID them in the lab
💊What are the treatment options (including mechanisms & resistance to anti-fungals)
#IDtwitter #MicroMedEd
🤔What are they
🤒Which ones cause human disease
🧫How do we ID them in the lab
💊What are the treatment options (including mechanisms & resistance to anti-fungals)
#IDtwitter #MicroMedEd
Yeast are a type of fungi (so are moulds&🍄).
"Yeast" isn't a taxonomic group, it describes how they appear. Single-celled like bacteria, but eukaryotic. (More here )
Thanks Saccharomyces for your sourdough bread. (And my beer🍻)
nature.com/articles/nrmic…
"Yeast" isn't a taxonomic group, it describes how they appear. Single-celled like bacteria, but eukaryotic. (More here )
Thanks Saccharomyces for your sourdough bread. (And my beer🍻)
nature.com/articles/nrmic…
Yeast come in many shapes & sizes, and there are mimics that can look like yeast on microscopy.
🔬The CLSI M54 categorizes yeast by size, and I love their approach, expanded here:
🔬The CLSI M54 categorizes yeast by size, and I love their approach, expanded here:
CASO CLINICO
Masc 33 años, consulta en Urgencias. Cefalea + nauseas + dism edo alerta + convulsión de 3 semanas. Exp: Rigidez nuca, 2 adenop cervicales 1 cm, Babinsky +.
Labs: Hb 7.8, Plq 178 mil, Leu 5.2; Cr 1.27 BUN 42. HIV test +.
Masc 33 años, consulta en Urgencias. Cefalea + nauseas + dism edo alerta + convulsión de 3 semanas. Exp: Rigidez nuca, 2 adenop cervicales 1 cm, Babinsky +.
Labs: Hb 7.8, Plq 178 mil, Leu 5.2; Cr 1.27 BUN 42. HIV test +.
Se realiza PL con LCR claro; PA 32 cmH2O; Cel 21; Glu 23 (Central 122); Prot 99.
Tinciones Gram/ZN/India Ink
Cultivo LCR/Hemo: En incubación
GeneXpert RIF assay en LCR neg
En la microscopia se encuentra la siguiente imagen.
Tinciones Gram/ZN/India Ink
Cultivo LCR/Hemo: En incubación
GeneXpert RIF assay en LCR neg
En la microscopia se encuentra la siguiente imagen.
¿Cuál es el mejor tratamiento que le podemos ofrecer a este paciente?
