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1/6 Our study comparing reactogenicity & immunogenicity of homologous (2xBNT/Pfizer) vs heterologous (AZ/ChAdOx +BNT) vaccination is available
medrxiv.org/content/10.110…

Great team effort @vmcorman #FlorianKurth #DavidHillus #TatjanaSchwarz #PinkusToberLau et al. @ChariteBerlin
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2/6 We report interim results of a prospective cohort study involving n=340 health care workers, comparing reactogenicity and immunogenicity of homologous BNT/BNT vs heterologous ChAdOx/BNT vaccination, at 3 and 10-12week intervals, respectively.
3/6 Both regimens were well-tolerated and safe. Local reactions were frequently reported for all vaccines. Systemic reactions, incl. severe reactions, were most frequent following ChAdOx prime immunisation. Reactogenicity of BNT/BNT & ChAdOx/BNT boosters were comparable.
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