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Task-free fMRI is governed by high-amplitude BOLD coactivations (termed "CAPs"). But how do these patterns emerge and what do they mean?
New collaborative work conceived by #Diego_Fasoli and #Stefano_Panzeri provides possible explanations 👉tinyurl.com/2p8un5kp

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In this work, we developed a large-scale network model of the mouse cortex that combines *directed* axonal connectivity (👉tinyurl.com/mryub799) with *non-linear* firing rate dynamics.

PS: “we” in this thread mostly stands for “Diego & Stefano”

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Our model reproduces remarkably well (ρ = 0.55) the topography of empirical 🐁 rsfMRI activity: simulated data show robust inter-hemispheric symmetry, and delineate well-characterized network systems of the mouse such a default-mode network, latero-cortical system etcetera.

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