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First, we must not let the tail wag the dog.
Which should one decide first?
Choose the endpoint, then calculate the sample size
or
Calculate the sample size, then choose the endpoint
Which should one decide first?
Choose the endpoint, then calculate the sample size
or
Calculate the sample size, then choose the endpoint
They are, of course, presented together so it is in simultaneous in PRESENTATION to the public but this Twitter group is for intelligent people who think about where knowledge comes from, not for soundbite-swallowers.
