Discover and read the best of Twitter Threads about #DrTJWrites
Most recents (2)
Last time we talked about what the top 5 antibiotic resistant infections are
Today we are gonna talk about what drives antibiotic resistance and current obstacles scientists face in curbing it
We’ll use this paper for reference: pubmed.ncbi.nlm.nih.gov/25859123/
#DrTJWrites
Today we are gonna talk about what drives antibiotic resistance and current obstacles scientists face in curbing it
We’ll use this paper for reference: pubmed.ncbi.nlm.nih.gov/25859123/
#DrTJWrites
We actually talked about antibiotics structure but y’all know what I meant 😂😂
Anyway, there are 4 crucial factors that drive antibiotic resistance:
*Human Overuse
*Inappropriate Prescribing
*Agricultural Overuse
*Lack of New Antibiotics being produced
Anyway, there are 4 crucial factors that drive antibiotic resistance:
*Human Overuse
*Inappropriate Prescribing
*Agricultural Overuse
*Lack of New Antibiotics being produced
1) Human Overuse
Alexander Fleming, founder of penicillin, warned about antibiotic overuse
“The public will demand the drug and then will begin an era of abuses”
Antibiotic overuse encourages
*Spontaneous genetic mutation
*Horizontal gene transfer (HGT)
*Unnatural Selection
Alexander Fleming, founder of penicillin, warned about antibiotic overuse
“The public will demand the drug and then will begin an era of abuses”
Antibiotic overuse encourages
*Spontaneous genetic mutation
*Horizontal gene transfer (HGT)
*Unnatural Selection
Now that you know what the top 5 antibiotic resistant infections are, let’s keep it goin and talk about the different classes of antibiotics and what they do
I’ll start by listing the top 10 generic antibiotics below 👇🏾
#DrTJWrites
I’ll start by listing the top 10 generic antibiotics below 👇🏾
#DrTJWrites
I’ll start by listing them below, then organizing them by structural class
1) amoxicillin
2) doxycycline
3) cephalexin
4) ciprofloxacin
5) clindamycin
6) metronidazole
7) azithromycin
8) sulfamethoxazole + trimethoprim
9) amoxicillin + clavulanate
10) levofloxacin
1) amoxicillin
2) doxycycline
3) cephalexin
4) ciprofloxacin
5) clindamycin
6) metronidazole
7) azithromycin
8) sulfamethoxazole + trimethoprim
9) amoxicillin + clavulanate
10) levofloxacin
Many of these are in different structural classes so let’s talk about those
A) Penicillins/β-lactams (amoxicillin)
These antibiotics are called β-lactams because of their structure
A lactam is an organic structure that is cyclic (fused ring) and contains nitrogen.
A) Penicillins/β-lactams (amoxicillin)
These antibiotics are called β-lactams because of their structure
A lactam is an organic structure that is cyclic (fused ring) and contains nitrogen.
