Discover and read the best of Twitter Threads about #DrugDevelopment

Most recents (10)

In May 2019, Dr. @rschilsky & I co-chaired the #AAADV19 Workshop Plenary Session "Decentralized #ClinicalTrials: The Future is Now." An incredible group of panelists from academia, industry, govt, & patient #advocacy šŸ‘‡discussed the rationale, challenges, & opportunities of DCTs. Image
No one knew yet that the #COVID19 #pandemic was just around the corner. In Mar 2020, FDA released a guidance on conduct of #clinicaltrials during the pandemic: fda.gov/media/136238/dā€¦, & colleagues wrote about the impact on #OncTwitter trials: ncbi.nlm.nih.gov/pmc/articles/Pā€¦. /2
FDA has now released a draft guidance on decentralized #clinicaltrials for drugs, biological products, & devices covering #telehealth, remote assessments, consent, shipping of IP, & more: fda.gov/media/167696/dā€¦. #MedTwitter #regulatory #drugdevelopment Image
Read 5 tweets
1/ $PVCTā€™s Modernized #SmallMolecule #RoseBengal: A #DrugSubstance, and #ActivePharmaceuticalIngredient for 21st Century #DrugDevelopment. A THREAD.
2/ ā€œEveryoneā€ seems to know or understand #RoseBengal, but do they (you) really?
3/ #RoseBengal is a small molecule (i.e., <1,000 Daltons*), but a ā€œheavyā€ one at 973.67 Da or g/mol. It is heavy because of its four iodides, which comprise 52% of its molecular weight.
Read 45 tweets
1/ A THREAD on what $PVCT achieved in 2022. #event #discovery #milestone #milepost. #rosebengal #rosebengalsodium.
2/ $PVCT 2023 Stockholder Letter (released January 9th). . #rosebengal #rosebengalsodium.
3/ $PVCT #clinical and #research collaborators made 6 presentations at 5 medical conferences about PV-10 for different cancers. #ENETS22 #AACR22 #ASCO22 #ISOO2022 #melanomabridge. #presentations. #rosebengal #rosebengalsodium.
Read 50 tweets
#Genomics is a rapidly growing field of #science that has revolutionized the way we understand #biology.
It has #applications in diverse fields. From #healthcare and #biotechnology to #climatechange, genomics is leading to some of the most exciting and world-changing discoveries in science and #medicine like:
1. Predicting Disease Risk:šŸ“Š

Genomics can detect diseases long before symptoms present themselves. Early #diagnosis of a disease can significantly increase the chances of successful treatments like #cancer, #diabetes, #autism, etc.
Read 8 tweets
Daily Bookmarks to GAVNetĀ 11/09/2021 greeneracresvaluenetwork.wordpress.com/2021/11/09/daiā€¦
The shifting sands of ā€˜gain-of-functionā€™ research

nature.com/articles/d4158ā€¦

#GainOfFunction #ResearchMethodology #ethics #narrative #consequences
Structure of a ā€˜promiscuousā€™ protein will help scientists design better drugs

phys.org/news/2021-11-pā€¦

#GutProtein #MolecularStructure #DrugDevelopment #DrugAbsorption #ResearchResults
Read 8 tweets
Syngene is delighted to share that we are part of Fortune Indiaā€™s Top 100 Wealth Creators list for 2021.
The criteria involved being a listed company with a 5-year CAGR of 7.5% plus in terms of market cap, revenue &profit (2017-21).
#FortuneIndia #Syngene #FortuneList #CDMO
1/5
Those incurring a net loss in any of the 5 fiscals (2016-20) were filtered out. The final 100 were based on firms having revenues of Rs 300 crores or more in FY20.
2/5
Key to our success has been our growing clientele who regard us more as a strategic partner with flexibility to work across a spectrum of clients -MNCs to start-ups. We also have a consistent client retention rate of 90%.

#strategicpartnership #clientele #USA #Europe #Japan
3/5
Read 5 tweets
(1/13) Please RT: our first #tweetorial!

Here's a šŸ§µon our new paper which is also my 1st time being (joint) last authorāœļø

Congrats to all, especially superstar med student @LuszczakSabina!

#AcademicTwitter @AcademicChatter @OpenAcademics #womeninSTEM

nature.com/articles/s4159ā€¦
(2/13) In #prostatecancer cell lines & human tissue, co-targeting #PIM & #PI3K #kinases seems promising!

We reckon ~20% of prostate cancer patients could benefit from this approach in future & these tend to be the sicker patients.

Scroll for #science!

nature.com/articles/s4159ā€¦
(3/13) Fig1a:

From publicly available data we see that some patients overexpress either the #PIM pathway, the #PI3K pathway, or both. Each of these targets have inhibitors in development, that could theoretically be of benefit to any of these patient groups when combined šŸ¤ž
Read 13 tweets
šŸ”ˆNEW BLOG POST ALERT šŸšØā£ā£
ā£ā£
Click our link to read our latest blog post on COVID-19 treatments and where weā€™re at with data. ā£ā£ā£ā£
ā£ā£
thesciencesocial.com/2020/05/05/covā€¦
ā£ā£
Give it a read and get back to us with your questions and comments āœØ Image
Image
Read 5 tweets
Thread: I am getting tons of msgs from fellows since a few recent talks at @hopkinskimmel, @SocTransOnc Fellows Forum, etc, + Twitter. I am happy to hear from all of you, esp the many people interested in #regulatory science. But many similar Qs, so here goes w/ resources!
@hopkinskimmel @SocTransOnc The #FDA_ASCOFellowsDay is a 1d workshop for #hematology & #oncology fellows in last yr (+ lim # of next to last yr) of training. It happens 2x/yr (fall & spring) on FDA campus in MD & 1x/yr at @ASCO Annual Mtg (1/2 day on Fri am). Applications for #ASCO20 one will open soon. 2/X
@hopkinskimmel @SocTransOnc @ASCO Our next one at the FDA campus is coming up on 3/10/20 (already full). This is a screenshot w/ high-level overview of it, and here's the link where you'll find application instructions for the next one once it opens in a few wks: asco.org/training-educaā€¦ 3/X
Read 9 tweets
I will now proceed to go on a #tweetrant / #tweetorial with regards to #Pharmaceutical #biotech pricing (focus on #cancer).

Very timely, also see @WSJ wsj.com/articles/big-pā€¦ on price hikes.

For the record, no #COI / #FCOI. Feel free to contribute to this discussion.
Lets look at the problem from the @PhRMA / business perspective. And lets suppose you are a wonderful company, started by wonderful people who just want to make the world a better place (I know, not real, but stay with me for a minute).
You start with a great idea / or pipeline platform and start selling this concept to #VC #VentureCapital, and lets assume that this is actually a really good idea. What is the needed return on investment to make this worth while. A: further R&D must exceed the cost of capital.
Read 17 tweets

Related hashtags

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!