Discover and read the best of Twitter Threads about #ECCMID22
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Late breaker session at #ECCMID2022 on acute hepatitis cases of unknown origin in children.
So far, 169 cases have been reported from 11 countries since first case was identified in 31 March. 17 have required liver transplant & at least one death has been reported. #IDTwitter
So far, 169 cases have been reported from 11 countries since first case was identified in 31 March. 17 have required liver transplant & at least one death has been reported. #IDTwitter
Almost all cases had high transaminases, majority of children have been hospitalised. No common exposure has been identified, no link to COVID19 vaccination. Adenovirus F41 was identified in several cases, but it doesn’t fully explain the clinical severity observed. #ECCMID2022
But there are still many uncertainties about acute hepatitis cases observed. Especially the # of cases, exact age group, clinical presentation, uncertain test results as not all cases were tested for adenovirus, risk factors and transmission routes remain unclear. #ECCMID2022
Quickly catching the special session on hepatitis of unknown aetiology at #ECCMID22 before heading back to Germany.
Aikaterini Mougkou of @ECDC_EU gives an update on cases in EU
Currently reported cases are higher than expected in Ireland and Netherlands, maybe Denmark.
Currently reported cases are higher than expected in Ireland and Netherlands, maybe Denmark.
@ECDC_EU Some of the limitations of the data:
- "it is unclear if there's underestimation of cases as not all countries have robust data systems and not all cases have been defined with the same criteria”
- "We do not know if there are children with subclinical presentation"
- "it is unclear if there's underestimation of cases as not all countries have robust data systems and not all cases have been defined with the same criteria”
- "We do not know if there are children with subclinical presentation"
