Discover and read the best of Twitter Threads about #EIDD1931
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This is a thread on use of drugs for #COVID19
Hydroxychloroquine (Lupus, RA) Lopinavir/Ritonavir (HIV/AIDS) Remdisivir and Favipiravir (Ebola) and Camostat (Pancreatitis, Japan) are drugs that seem to have activity against SARSCov2
Some of these are used on Emergency Basis. 1/n
Hydroxychloroquine (Lupus, RA) Lopinavir/Ritonavir (HIV/AIDS) Remdisivir and Favipiravir (Ebola) and Camostat (Pancreatitis, Japan) are drugs that seem to have activity against SARSCov2
Some of these are used on Emergency Basis. 1/n
Potent nucleoside antiviral drug from Emory University shows broad spectrum activity against corona viruses including Remdisivir resistant strains. Acts by targeting RdRp to increase RNA mutation rates. @EmoryUniversity #EIDD2801 #COVID19
#coronavirus 1/n
news.emory.edu/stories/2020/0…
#coronavirus 1/n
news.emory.edu/stories/2020/0…
Promising broad spectrum antiviral agent #EIDD2801 is active against #Remdisivir resistant strains. Indeed such mutations increase susceptibility which augurs well for combination use. It’s a prodrug gets converted to #EIDD1931 & increase mutations.
2/n
biorxiv.org/content/10.110…
2/n
biorxiv.org/content/10.110…
