Discover and read the best of Twitter Threads about #ESCAPE
Most recents (10)
Diese #Herbstwelle wird #keine klassische #Varianten-#Welle, wie die 6 Wellen zuvor (2xD614G, B.1.1.7, Delta, BA.1, BA.2, BA.4/5) sondern wir sehen alle möglichen BA.2 Sublinien, die alle die gleichen Mutationen aufweisen (493 Reversion An Position 346 444 452, 460, 486 /1
Es entsteht eine Situation, die die Wissenschaftler so zuvor bei SARS-CoV2 vorher noch nie beobachtet hatten: konvergente Evolution überall weltweit, immer die gleichen Mutationen = koplett unübersichtliche Lage. "Something #big ist happening with SC2, /2
Absolute Leseempfehlung für diesen Thread von @shay_fleishon ⤵️wenn jemand da näher einsteigen will. Fakt ist dass dies eine für die Pandemie völlig #neue #Situation : #Überall ploppen #Subvarianten und Second-Generation Varianten von BA.2 und BA.5 auf,
/3
/3
No #sane man would live with a #ViolenceProne, #PhysicallyAbusive #woman, with a #Femdom, #Gynarchy based ideology, who's built like a #tank and #ScaresTheShit out of every man she encounters!
So whoever you are & wherever you are, your life must be lonely.
Please come to me!
So whoever you are & wherever you are, your life must be lonely.
Please come to me!
Because, while no #sane man would want you, this clearly bonkers chap longs for an #assertive, #giantess of a #woman, with #MusclesOfSteel, who can make any fan of #NamioHarukawa's art work so week at the knees, he would virtually pine away with longing for her!
I know that, if I lived in such an #AbusiveRelationship, I'd want to #escape.
However, I don't live in an #abusive #relationship & I have the luxury of longing for a #powerful, #violent, #dominant & #controlling #woman who wants to #TotallyEnslave me, from whom #ThereIsNoEscape!
However, I don't live in an #abusive #relationship & I have the luxury of longing for a #powerful, #violent, #dominant & #controlling #woman who wants to #TotallyEnslave me, from whom #ThereIsNoEscape!
#Impfstoffe, #Booster #Covax & #Kommunikation:
1) #AstraZeneca: #EMA STIKO und #Massenmedien, haben diesen Impfstoff so #kaputt #geredet, dass er ab Juli mehr unter die Leute zu bringen war. Es musste verdammt viel #weggeschmissen worden, statt #kreuzgeimpft (AZ+mRNA)
1/x
1) #AstraZeneca: #EMA STIKO und #Massenmedien, haben diesen Impfstoff so #kaputt #geredet, dass er ab Juli mehr unter die Leute zu bringen war. Es musste verdammt viel #weggeschmissen worden, statt #kreuzgeimpft (AZ+mRNA)
1/x
Obwohl sich abgezeichnet hat, dass eine #Erstimpfung mit #AstraZeneca und eine zeitlich verzögerte #zweite_Impfung mit einem mRNA Impfstoff, einer 2xmRNA Impfung mindestens gleichwertig ist, wurde dieses #heterologe_Impfschema kaum angewendet, da keine STIKO Empfehlung.
2/x
2/x
Die Schutzwirkung durch das #heterologe_Prime_Boost_Schema mit AZ + mRNA / #Kreuzimpfung, ist höher, und hält deutlich länger an als zweimal AZ
Dennoch hat man zweimal AZ mit kurzem Abstand zwischen beiden Dosen an Die verimpft, die überhaupt noch AZ imfwillig.
3/x
Dennoch hat man zweimal AZ mit kurzem Abstand zwischen beiden Dosen an Die verimpft, die überhaupt noch AZ imfwillig.
3/x
In the latest issue! Be sure to explore this exciting research about #SARSCoV2 variants and their #escape from #immune response
bit.ly/3e2QxoP
For all @CellPressNews #coronavirus research and commentary, visit cell.com/2019-nCOV
#COVID19
🔽🔽🔽
bit.ly/3e2QxoP
For all @CellPressNews #coronavirus research and commentary, visit cell.com/2019-nCOV
#COVID19
🔽🔽🔽
Mutations in the #SARSCoV2 spike #protein result in tighter binding to the #ACE2 receptor and allow escape from monoclonal #antibody neutralization. Online now! @UniofOxford
bit.ly/3nzukSI
bit.ly/3nzukSI
The 501Y.V2 #variant of #SARSCoV2 exhibits resistance to neutralization from monoclonal #antibodies and sera from convalescent as well as #immunized individuals
bit.ly/3xxMrNe
bit.ly/3xxMrNe
New insights into SARS-CoV-2 immune evasion
#SARS-CoV-2 #mutations can lead to antibody #escape. What about T cells? In our study in @SciImmunology we report how mutated epitopes evade T cell responses.
immunology.sciencemag.org/content/6/57/e… 1/7
#SARS-CoV-2 #mutations can lead to antibody #escape. What about T cells? In our study in @SciImmunology we report how mutated epitopes evade T cell responses.
immunology.sciencemag.org/content/6/57/e… 1/7
Using deep viral sequencing we identified low-frequency mutations in experimentally validated CD8 T cell epitopes of SARS-CoV-2, some of which were found as fixed mutations in global virus sequences from @GISAID. 2/7
Guided by binding predictions we selected epitopes and #mutants for further biochemical investigations by cell-free MHC-I binding assays. These analyses suggested that single amino acid changes impair binding to MHC-I molecules. 3/7
As a team of scientists from @scrippsresearch @karolinskainst @UniBonn @UniklinikBonn @IIIBonn @uni_tue @Illinois_Alma, we identified four potent neutralizing camelid nanobodies ...
Solved the #Xray structure of all four #nanobodies in complex with #SARSCoV2 spike #RBD @wchnihcholas and Ian Wilson ...
Used #CryoEM to determine that VHH E stabilizes the 3-up conformation of trimeric #SARSCoV2 spike @BMartinHallberg ...
Infinite Spiders, playwright, @johnsteppling
"If you go to, say, Amazon and under books type in #Philosophy, or Philosophy/Truth…you will get a litany of books with the phrase “post #truth” in the title. It is, apparently, a #posttruth world now."
john-steppling.com/2020/12/infini…
"If you go to, say, Amazon and under books type in #Philosophy, or Philosophy/Truth…you will get a litany of books with the phrase “post #truth” in the title. It is, apparently, a #posttruth world now."
john-steppling.com/2020/12/infini…
"This is related to what I experience as absent in daily life. Post truth is post experience in some sense. As Cory Morningstar put it in our podcast (#25); 'we are being reprogrammed'."
[#SocialEngineerring - a prerequisite for transition to #4IR]
[#SocialEngineerring - a prerequisite for transition to #4IR]
"Of course the more profound elements of the #reprogramming are to be found in the #digital revolution. There is no way to overemphasize the impact of the internet & its various platforms....
Societies of the west are increasingly demoralized...."
Societies of the west are increasingly demoralized...."
A THREAD on heat.
A personal view on how cities should react on #ClimateChange and #heatisland effect.
A personal view on how cities should react on #ClimateChange and #heatisland effect.
#Proportion
Most important is proportion. The hotter the climate the narrower the streets are. There are reasons why streets around the mediterranean are narrower than they are typically in germany.
Most important is proportion. The hotter the climate the narrower the streets are. There are reasons why streets around the mediterranean are narrower than they are typically in germany.
There is an unlucky proportion where the buildings are not narrow enough to provide shade but too close together to let the heat radiate away at night. It depends on orientation, latitude, weather at night. Not easy. Historical streets have mostly good proportions by trial.
#ChinaPneumonia —
NO people in #Wuhan🇨🇳 is allowed to leave starting 23 Jan 10am!
The whole city is being #quarantined — Train stations & #Airport shut; Bus, subway closed; Roads blocked by #police.
#WuhanPneumonia #China
#coronavirus #AntiCCP
NO people in #Wuhan🇨🇳 is allowed to leave starting 23 Jan 10am!
The whole city is being #quarantined — Train stations & #Airport shut; Bus, subway closed; Roads blocked by #police.
#WuhanPneumonia #China
#coronavirus #AntiCCP
#WuhanCoronavirus🇨🇳
— With the WHOLE city locked down from today, people in #Wuhan start FIGHTING for #food & daily supplies in local supermarkets 😱
No wonder #CCPChina is sending out #army to guard major Train Stations & Airport!
#ChinaPneumonia #ChinaVirus
#Wuhan #WuhanSARS
— With the WHOLE city locked down from today, people in #Wuhan start FIGHTING for #food & daily supplies in local supermarkets 😱
No wonder #CCPChina is sending out #army to guard major Train Stations & Airport!
#ChinaPneumonia #ChinaVirus
#Wuhan #WuhanSARS
🇨🇳#WuhanCoronavirus —
#Chinese Army/ Security officers guarding major #Wuha train station, Hankou high-speed rail station to prevent ppl from leaving!
Citywide *lockdown* but some still managed to #ESCAPE!
#ChinaPneumonia #China
#coronovirus #GodBless
#Chinese Army/ Security officers guarding major #Wuha train station, Hankou high-speed rail station to prevent ppl from leaving!
Citywide *lockdown* but some still managed to #ESCAPE!
#ChinaPneumonia #China
#coronovirus #GodBless
Have only read 1 chapter of "Escape" by Manjula Padmanabhan but, boy, is it promising!
Is this going to be a story rivaling Rosemary's baby or The Stepford wives which uses horror as a medium for social commentary on the role of women in society?
Is this going to be a story rivaling Rosemary's baby or The Stepford wives which uses horror as a medium for social commentary on the role of women in society?
Well, it was a great premise, I must admit. The characters, too, were powerful. But it falters quite a bit in execution as it suffers from bad pacing and a flat climax. It reclaims itself a little bit towards the very end but not enough. (3 out of 5)
Escape by Manjula Padmanabhan has the makings of a very good story. In a futuristic India, women (or "vermin") are completely eradicated when another means of child-rearing is discovered.
