Discover and read the best of Twitter Threads about #ESICMphysio
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Thematic talk today about the ROLE of RCTs in Intensive Care Medicine. **TWEETORIAL** #ESICMphysio #FOAMed #FOAMcc
Randomised controlled trials (RCTs) are the most rigorous way of determining whether a cause-effect relation exists between treatment and outcome and are an integral component in the hierarchy of evidence which guide current clinical practice. #ESICMphysio ... but...
There are some problems... ncbi.nlm.nih.gov/pubmed/20413119 
Today we're going to take a look at BIOENERGETICS in ICU in this quick Tweetorial :-) #ESICMphysio #FOAMed #FOAMcc
Bioenergetics = biochemistry concerned with the energy involved in making and breaking of chemical bonds in the molecules found in biological organisms. It can also be defined as the study of energy relationships and energy transformations and transductions. #ESICMphysio
Mitochondrial functions incl production of energy, activation of programmed cell death, and a number of cell specific tasks, e.g., cell signaling, control of Ca2+ metabolism, and synthesis of a number of important biomolecules. ncbi.nlm.nih.gov/pmc/articles/P…
So - the candidates from #ESICMphysio are off to engage in their workshops - so I thought... let's hold a virtual workshop here on MECHANICAL VENTILATION! #FOAMed @ESICM
Let's start off at the very beginning. This is a HUGE topic... obviously not going to cover everything. But let's start off at the very beginning and look at my Tweetorial from yday from Prof Barnes talk on the physics of ventilation... #ESICMphysio
@MedCramVideos do a REALLY good series for beginners - for free - on YouTube - 5+ videos on Ventilators and how they work: youtube.com/results?search…
The amazing @icu_nivare gives a talk on HOMEOSTASIS in ICM! Here is my Tweetorial on his brilliant talk. #FOAMed #ESICMphysio IT'S ALL ABOUT BALANCE.
A brilliant overview of OSMOREGULATION and VOLUME REGULATION. #ESICMphysio
@susannaprice gives us a whirlwind tour of VENOUS RETURN. Going back to basics is vitally important. This is her talk in the form of a Tweetorial at #ESICMphysio #FOAMed - don't forget to get involved in the conversation! #POCUS
"When asking about the RIGHT heart... Which RIGHT heart do you mean?" Normal? Pathological? It's complicated... #FOAMed #ESICMphysio
Starling = what goes in 'must' (hopefully) come out. Although venous return leads to COutput; COutput must dictate venous return! BOTH must be equal.... or it can't quite 'flow'.... #ESICMphysio
The fantastic Prof Tom Barnes gave us a talk today on the PHYSICS of mechanical ventilation. This is his material via @ESICM #ESICMphysio in the form of a Tweetorial :) #FOAMed THREAD BELOW --> (continued...)
and so we start... Physics can tell us an awful lot about the way our bodies work - but it's SO different from clean 'physics' - this is applied physics. All patients lungs are different. These concepts however are vital to understanding key issues in ventilation.
Lung damage can amplify from the smallest of initial injuries. Positive feedback ++. Damage begets damage. This is why we try to mitigate pressures in our vent settings. #ESICMphysio Question is tho... how can we do it better?
Before our LUNG sessions today... a quick look at what we already know about PPV and PEEP in ICU... #ESICMphysio #FOAMed
We've been looking at MV for decades. In 1986 - a good summary was published about its deleterious effects... Life saving yes, but nurses and doctors agreed it came with profound sequelae... #FOAMed #ESICMphysio ncbi.nlm.nih.gov/pubmed/9564354 and ncbi.nlm.nih.gov/pubmed/3530039
In 2008 a great reflection was published in BJA - which did summarise that "Ventilation with PEEP is a proven, effective modality in both anaesthesia and ICU, despite the immense physiological derangement it causes" #ESICMphysio academic.oup.com/bja/article/10…
