Discover and read the best of Twitter Threads about #ElectronMicroscopy

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Different cell types in the brain have their own connectivity rules and patterns. In a recently published study, our #neuroscience researchers took a deep dive into the connectomics of an important but enigmatic cell type, the chandelier cell. 🧵1

📄 elifesciences.org/articles/73783
🔬 💻 Using large-scale #electronmicroscopy with automated segmentation, we mapped the complete axo-axonic input onto pyramidal neurons (1,929 synapses in total, 1,127 from chandelier cells) in a volume of layer 2/3 of mouse visual cortex. #ImagingTheFuture #BrainMapping🧵2
By completely reconstructing the presynaptic chandelier cells, we found a novel principle of connectivity, where a group of interneurons are essentially interchangeable, but their postsynaptic targets individually regulate the amount of input they receive from the population. 🧵3
Read 7 tweets
Fish Farming Is Feeding the Globe. What’s the Cost for Locals? | The New Yorker

newyorker.com/magazine/2021/…

#farming #fisheries
Researchers report new approach to cultured meat

phys.org/news/2021-03-a…

#meat #artificial
Read 10 tweets
A study led by the brilliant @ShelFarFar shows that viral transmission to placenta occurred in a woman at 22 wks of pregnancy. Heroic efforts by our @YaleMSTP student Alice Lu found the major target of #SARSCoV2 to be the #syncytiotrophoblasts 👇🏽 (1/n)

medrxiv.org/content/10.110…
An accompanying #ElectronMicroscopy analysis by Yuki Yasumoto & Tamas Horvath shows beautiful images of the #SARSCoV2 in the syncytiotrophoblasts. (2/n)
Shown by @VogelsChantal & @NathanGrubaugh, the mother had detectable levels of #SARSCoV2 in her saliva and urine, but not in her blood. However, the level of virus in the placenta was sky high. How did the virus get to the placenta? (3/n)
Read 6 tweets
1/ Coronavirus SARS-CoV-2 attached to cilia of human respiratory epithelial cell. This is one of the very first images of the SARS-CoV-2 virus isolated from patients.
2/ reproduced conditions of infection in a reconstituted human respiratory epithelium model cultivated at the air/liquid interface. This physiological model was developed and provided by the company Epithelix #COVID2019 #pathology #electronmicroscopy #virus
3/ Cette image a été obtenue par microscopie électronique à transmission sur la plateforme d’imagerie de l'Université Claude Bernard Lyon 1 (CIQLE). Crédits: #virpath Manuel Rosa-Calatrava, Olivier Terrier, Andres Pizzorno, Elisabeth ERRAZURIZ-CERDA.
Read 3 tweets

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