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Images of Infectious Diseases
This is the peripheral blood smear of a 71M s/p splenectomy. Rural Wisconsin. No travel.
CC: fever, sweats, dyspnea
ROS: dark urine
PE: jaundice
Hgb 10. Low haptoglobin.
TBI 3.3 LDH 1075
What is the diagnosis and recommended Rx?
#MayoIDQ MCQ next
This is the peripheral blood smear of a 71M s/p splenectomy. Rural Wisconsin. No travel.
CC: fever, sweats, dyspnea
ROS: dark urine
PE: jaundice
Hgb 10. Low haptoglobin.
TBI 3.3 LDH 1075
What is the diagnosis and recommended Rx?
#MayoIDQ MCQ next
1/
71M. WI. (see prior tweet)
S/p splenectomy.
Fever, jaundice, hemolytic anemia.
Your diagnosis: babesiosis (parasitemia 7.3%).
3 days after starting Rx: tinnitus and hypoacusis
What Rx most likely caused this adverse effect?
71M. WI. (see prior tweet)
S/p splenectomy.
Fever, jaundice, hemolytic anemia.
Your diagnosis: babesiosis (parasitemia 7.3%).
3 days after starting Rx: tinnitus and hypoacusis
What Rx most likely caused this adverse effect?
2/
Treatment of #Babesiosis
1. Atovaquone-azithromycin
2. Quinine-clindamycin
The two regimens have comparable efficacy in non-life-threatening babesiosis.
BUT safety profile of Atovaquone-azithromycin was better
nejm.org/doi/full/10.10…
Treatment of #Babesiosis
1. Atovaquone-azithromycin
2. Quinine-clindamycin
The two regimens have comparable efficacy in non-life-threatening babesiosis.
BUT safety profile of Atovaquone-azithromycin was better
nejm.org/doi/full/10.10…
