Discover and read the best of Twitter Threads about #FlorianKurth

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Unsere neueste Studie zeigt, dass die Immunantwort nach Biontech-Impfung bei älteren menschen im Vgl. zu Jüngeren deutlich verzögert & insgesamt etwas abgeschwächt ist.
@ChariteBerlin @vmcorman #FlorianKurth #PinkusTuberLau #TatjanaSchwarz
wwwnc.cdc.gov/eid/article/27…
In einigen Fällen kann es zu Ausbrüchen unter alten Menschen in Pflegeeinrichtungen kommen, trotz vollständiger Impfung. Allerdings ist der Krankheitsverlauf i.d.R. milde(r).
Wichtig ist v.a. die Impfung von Pflegepersonal & Kontaktpersonen.
wwwnc.cdc.gov/eid/article/27…
Die Ergebnisse passen auch zur jüngsten Studie @TheLancet zur Antikörperantwort nach Impfung. Reduzierte Neutralisation von VOC Beta & Delta, sowie Abnahme der Neutralisationstiter mit dem Alter.
sciencedirect.com/science/articl…
Read 6 tweets
1/6 Our study comparing reactogenicity & immunogenicity of homologous (2xBNT/Pfizer) vs heterologous (AZ/ChAdOx +BNT) vaccination is available
medrxiv.org/content/10.110…

Great team effort @vmcorman #FlorianKurth #DavidHillus #TatjanaSchwarz #PinkusToberLau et al. @ChariteBerlin
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2/6 We report interim results of a prospective cohort study involving n=340 health care workers, comparing reactogenicity and immunogenicity of homologous BNT/BNT vs heterologous ChAdOx/BNT vaccination, at 3 and 10-12week intervals, respectively.
3/6 Both regimens were well-tolerated and safe. Local reactions were frequently reported for all vaccines. Systemic reactions, incl. severe reactions, were most frequent following ChAdOx prime immunisation. Reactogenicity of BNT/BNT & ChAdOx/BNT boosters were comparable.
Read 6 tweets

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