Discover and read the best of Twitter Threads about #GS5245

Most recents (2)

Hopes for the new year: #LongCovid trials I'm excited about

🧵
1) #CPCOV03

Host directed antiviral, induced autophagy

I wrote a thread about it here
2) #TVG489

Allogenic CAR T cells

These will hopefully be able to clear infected cells, if T cell evasion by SARS-CoV-2 (via MHC I downregulation) can be overcome

labiotech.eu/trends-news/te…
Read 11 tweets
When did @GileadSciences decide that #GS441524 hypothesis was valid? Clues in patent history🔍

While Gilead bashed GS-441524 in 2020, they quietly worked on oral prodrugs

Could we have had an oral COVID pill in late '20/early '21? 💊

I think YES 🧵1/16
worldwide.espacenet.com/patent/search?…
Patent on oral GS-441524 prodrugs has 1st priority filing on AUGUST 27, 2020. So they did not think the '524 hypothesis was worthless in 2020. 2/16
statnews.com/2020/05/14/gil…
Context: @Muller_Lab & I published an Opinion in @statnews urging Gilead to pursue dev of #GS441524 in May 2020 (above)

On June 24, 2020, we first met w Gilead science leadership, who indicated they were not interested. 3/16
medium.com/@victoriacyani…
Read 16 tweets

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