Discover and read the best of Twitter Threads about #GastonRamon
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In this new Commentary, @SaadOmer3 and I discuss the birth & evolution of vaccine science, how vaccinations have changed our world, the current state of vaccines, remaining challenges & future outlook. #VaccinesSaveLives (1/n)
cell.com/cell/fulltext/…
cell.com/cell/fulltext/…
Live attenuated vaccines worked well by themselves. But, immunization using toxoid alone induced poor immunity. #GastonRamon found that toxoid injected with ‘stuff’ incl. tapioca, lecithin, agar, starch oil, saponin or breadcrumbs improved immunity. (2/n)
tandfonline.com/doi/full/10.10…
tandfonline.com/doi/full/10.10…
While Alum became the adjuvant used in vaccines for past 100 years, there is a recent expansion in new adjuvants with potent capacity to boost immunity to vaccines. Discovery of pattern recognition receptors and their ligands laid foundation for this👇🏽 @YaleIBIO (3/n) 
