Discover and read the best of Twitter Threads about #GenBank

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This thread is #Genbank records regarding #MN908947. Evidence only, any further analysis upon this record subjects to individuals' own discretion. So, let's roll.
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Read 52 tweets
#UnAnnoFa il #genoma di "un #coronavirus" ricavato da un caso relativo al "focolaio di malattie respiratorie di #Wuhan" veniva pubblicato su #GenBank... 🧐#SARSCoV2
#UnAnnoFa... "Il focolaio di infezioni ha indotto timori di una potenziale epidemia dopo che la Cina ha dichiarato che il virus che lo ha causato è sconosciuto, ma proveniente dalla stessa famiglia di virus che ha causato le epidemie di #SARS e #MERS".🧐
reut.rs/36JSBvU
#UnAnnoFa Diventa improvvisamente chiaro che il nuovo virus viaggia velocemente... in aereo. Nessun campanello di allarme in giro per il mondo? 🧐 #covid19
cidrap.umn.edu/news-perspecti…
Read 87 tweets
#OneYearAgo a "coronavirus #genome from a case of a respiratory disease from the #Wuhan outbreak" was published on #GenBank... 🧐#SARSCoV2
#OneYearAgo "The cluster of infections had raised fears of a potential epidemic after China said last week that the virus causing it was a previously unknown type but came from the same family of viruses that caused the #SARS and #MERS epidemics".🧐
reuters.com/article/us-hea…
#OneYearAgo It was suddenly clear that the virus was travelling fast... any bell ringing?🧐#covid19
cidrap.umn.edu/news-perspecti…
Read 75 tweets
"The live SARS-like coronavirus SL-CoV-WIV1 has been isolated for the first time from bat droppings; and such virus has been confirmed to invade the host cells through the ACE2 of human beings..." ImageImageImage
Bat Severe Acute Respiratory Syndrome-Like Coronavirus WIV1
Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response. (2016) #ZhengLiShi #PeterDaszak #EcoHealth
Funding: #NIAID 110964 ImageImageImageImage
In this study, we have developed a fast and cost-effective method
for reverse genetics of coronaviruses by combining two approaches developed by others..As the genomes can be divided into multiple short fragments, mutations can be introduced into individual
fragments easily. ImageImageImageImage
Read 68 tweets
If anyone wants to investigate for themselves, here are all of the similar sequences to #SARSCoV2, #SARSCoV1, and #DISEASEXXX, a dog coronavirus. Note that #MERSCoV is ~64% similar to SARS-COV-2 and SARS-CoV2 is 80% similar to SARS-CoV-1.

These were download from @NIH #GenBank.
#SARSCoV2 ALIGNMENTS BY PERCENT IDENTITY NCBI Blast_(4) - ref_NC_045512.2_

docsend.com/view/s4w63k2uh…
#SARSCoV1 ALIGN NCBI Blast_NC_004718_SARS coronavirus, complete genome

docsend.com/view/atm8jub6h…
Read 13 tweets
As a scientist, I'd like to note that it's impossible to study a bat coronavirus for 7 years within a research lab where they were known to recombine different viral fragments, and not end up having evolution happen that perhaps wouldn't have happened in the wild. Just saying.
Recombining viruses, you say? Wuhan, 2017.

Hu, B., Zeng, L. P., Yang, X. L., Ge, X. Y., Zhang, W., Li, B., ... & Luo, D. S. (2017). Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus. PLoS pathogens, 13(11).
Read 6 tweets

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