Discover and read the best of Twitter Threads about #Gout
Most recents (11)
1a) Welcome to a live-tweeted, #accredited #tweetorial from @nationallipid #NLA23 in #Atlanta on advances in #hyperlipidemia management #LLT. Our expert returning faculty is Pam R. Taub, MD @PamTaubMD #cardiologist from @UCSDHealth 
1b) Dr. Taub is a clinician/scientist and is a frequent contributor to our #accredited programs. She is the founding director of the Step Family Foundation Cardiac Rehabilitation and Wellness Center at #UCSD.
#FOAMed #cardiotwitter @MedTweetorials #MedEd #lipids
#FOAMed #cardiotwitter @MedTweetorials #MedEd #lipids
2) This program is supported by an educational grant from Esperion Therapeutics & is intended for #HCPs. Statement of accreditation & faculty disclosures at cardiometabolic-ce.com/disclosures/. Earn 0.75 hr 🆓CE/#CME by following this 🧵!
😣Patient: "All my joints are painful & swollen!"😣
👩⚕️But when you examine the patient, you don't find any joint swelling
How to approach this scenario? 🤷
#MedTwitter #RheumTwitter #MedEd 🧵🧵🧵
(1/10)
👩⚕️But when you examine the patient, you don't find any joint swelling
How to approach this scenario? 🤷
#MedTwitter #RheumTwitter #MedEd 🧵🧵🧵
(1/10)
Now there are two possibilities
1️⃣ There was a joint swelling which is no longer there
OR
2️⃣ There was no joint swelling to begin with
(2/10)
1️⃣ There was a joint swelling which is no longer there
OR
2️⃣ There was no joint swelling to begin with
(2/10)
Let's start with the first one– there was indeed joint swelling which is no longer there
That means we are dealing with
☝️ An episodic inflammatory disease
✌️ Drug modified disease
(3/10)
That means we are dealing with
☝️ An episodic inflammatory disease
✌️ Drug modified disease
(3/10)
The #gout mega GWAS will be presented by @TonyMerriman2 *on behalf of a very large team* at the third plenary session
#ACR22
#ACR22
#ACR22 plenary highlights
1️⃣acrabstracts.org/sessions/plena…
2️⃣acrabstracts.org/sessions/plena…
3️⃣acrabstracts.org/sessions/plena…
1️⃣acrabstracts.org/sessions/plena…
2️⃣acrabstracts.org/sessions/plena…
3️⃣acrabstracts.org/sessions/plena…
🌟Abs 0001 Botson, et al.
MIRROR RCT: adding MTX to pegloticase for gout
👉52 wk results: response 60% vs 31% pbo
*response: SU<6mg/dl for >=80% of wks 48-52
#ACR22
MIRROR RCT: adding MTX to pegloticase for gout
👉52 wk results: response 60% vs 31% pbo
*response: SU<6mg/dl for >=80% of wks 48-52
#ACR22
1) I am a big fan of evolutionary medicine --> the study of human evolution and how it can be harnessed for the practice of medicine.
I recently went in for a deep dive into an important topic --> HYPERURICEMIA
Here is what I learnt!
I recently went in for a deep dive into an important topic --> HYPERURICEMIA
Here is what I learnt!
2) Uric acid is the endproduct of purine metabolism in humans --> this is an exception among mammals!
Why does this happen?
1. Lack of uricase
2. Avid renal reabsorption of uric acid
Why does this happen?
1. Lack of uricase
2. Avid renal reabsorption of uric acid
3) Why happened to uricase?
This ancient enzyme, present since bacteria, accumulated a number of mutations approx 10-30 million years ago and gradually lost its function in humans, some higher primates and some New World monkeys.
pubmed.ncbi.nlm.nih.gov/11961098/
This ancient enzyme, present since bacteria, accumulated a number of mutations approx 10-30 million years ago and gradually lost its function in humans, some higher primates and some New World monkeys.
pubmed.ncbi.nlm.nih.gov/11961098/
"Your diagnosis is elevated uric acid. You need to stop eating 🍅🥗🥦🥪🥩🫘, basically everything"
Beware of these!!
Elevated uric acid doesn't always 🟰 gout
#MedEd #MedTwitter #gout #Uricacid
Beware of these!!
Elevated uric acid doesn't always 🟰 gout
#MedEd #MedTwitter #gout #Uricacid
Gout is a form of arthritis due to deposition of excess uric acid in joints and it usually has (not always) high serum uric acid levels.
If one has gout, then avoid:
🍺 Alcohol
🥩 Red meat
🧃 packed juices, carbonated drinks (high fructose corn syp)
🍺 Alcohol
🥩 Red meat
🧃 packed juices, carbonated drinks (high fructose corn syp)
Join us tomorrow for the launch of a new #accredited #tweetorial on the primary care management of #hyperlipidemia covering the relationship between #LDL_C & major #CV events, CV risk categories, recommended LDL-C treatment goals, & oral therapeutic options for lipid-lowering
1) Welcome to a new #tweetorial on the primary care management of #hyperlipidemia. Our returning @cardiomet_CE expert author is dedicated #SoMe education advocate Kevin Fernando, FRCGP FRCP Edin, FAcadMEd MSc Diabetes @drkevinfernando
2a) This is the next instalment of @cardiomet_CE's 10-part #tweetorial foundational series on #lipid management! It is accredited for #CME/CE and intended for #physicians #physicianassociates #nurses #nursepractitioners #pharmacists.
#FOAMed @MedTweetorials #cardiotwitter
#FOAMed @MedTweetorials #cardiotwitter
À la question du pourquoi achetez-vous l’#eau en bouteilles plastiques, beaucoup répondent le goût :
Et selon les enquêtes d’opinion, qui valent ce qu’elles valent [CaD un peu, mais pas beaucoup non plus], c’est exactement ca :
ipsos.com/fr-fr/les-fran…
ipsos.com/fr-fr/les-fran…
Cependant, cette revue de l’histoire de la consommation d’eau en bouteille en France révèle qu’il s'agit d’un mouvement datant du début du 20ᵉ siècle qui s'est épanoui pour différente façon … dont la concurrence des embouteilleurs pour vendre plus.
cairn.info/revue-vingtiem…
cairn.info/revue-vingtiem…
1/ If there's some joint pain
In your neighborhood
Who you gonna call? 📞
🤯GOUT BUSTERS 👩⚕️
PGY-1 @Jen_LS_Hanberg gave a talk on
💊Urate-Lowering Therapy (ULT)💊
Let's review some pearls!
@MeganLockwoodMD @MGH_MSUS #MedTwitter #RheumTwitter #Nephtwitter #Gout
In your neighborhood
Who you gonna call? 📞
🤯GOUT BUSTERS 👩⚕️
PGY-1 @Jen_LS_Hanberg gave a talk on
💊Urate-Lowering Therapy (ULT)💊
Let's review some pearls!
@MeganLockwoodMD @MGH_MSUS #MedTwitter #RheumTwitter #Nephtwitter #Gout
2/ Who gets ULT?
The strongest indication is for patients with:
✅2 or more flares annually
✅Radiographic damage due to gout
✅TOPHI
The strongest indication is for patients with:
✅2 or more flares annually
✅Radiographic damage due to gout
✅TOPHI
3/ What are your ULT options? Check out the awesome slide below.
Takeaways:
💊Start with allopurinol! It will give you the biggest bang for your buck
💊Your target UA level is 6⃣- titrate q2-4 weeks
💊Start prophylactic therapy at the same time (NSAID, colchicine, pred)
Takeaways:
💊Start with allopurinol! It will give you the biggest bang for your buck
💊Your target UA level is 6⃣- titrate q2-4 weeks
💊Start prophylactic therapy at the same time (NSAID, colchicine, pred)
1/6 #Thread #IlsSachentNousChassons
Il y'a la #Chasse et l'après-chasse avec le traitement de la #venaison🤷♂️
Une fois éviscéré, le #gibier est, de préférence, conservé 48H au frigo dans la peau
Vient alors le temps du #dépeçage
Exemple ici : un #sanglier
Il y'a la #Chasse et l'après-chasse avec le traitement de la #venaison🤷♂️
Une fois éviscéré, le #gibier est, de préférence, conservé 48H au frigo dans la peau
Vient alors le temps du #dépeçage
Exemple ici : un #sanglier
2/6
Après le #dépeçage, la #découpe intervient et se réalise en fonction de vos souhaits de transformation et de consommation de la #venaison 🤤
Un cuissot de #sanglier à sécher, cela vous tente ?
#Recette #Gastronomie #MadeInFrance #Cuisine #Gibier
Après le #dépeçage, la #découpe intervient et se réalise en fonction de vos souhaits de transformation et de consommation de la #venaison 🤤
Un cuissot de #sanglier à sécher, cela vous tente ?
#Recette #Gastronomie #MadeInFrance #Cuisine #Gibier
3/6
La découpe du #gibier continue avec la préparation d'un #rôti avec les côtes filets désossées et les filets, le tout bardé et ficelé
La #poitrine et les #joues servent à faire la fameuse #daube de #sanglier
#Recette #Gastronomie #MadeInFrance #Cuisine
La découpe du #gibier continue avec la préparation d'un #rôti avec les côtes filets désossées et les filets, le tout bardé et ficelé
La #poitrine et les #joues servent à faire la fameuse #daube de #sanglier
#Recette #Gastronomie #MadeInFrance #Cuisine
🚨 Watch out, time for another #cholesterol #tweetorial! 🚨This time we’re going to take a look at the very fundamental nature of cholesterol molecule. It has biochemical properties that make it 1) essential to life but 2) problematic in excess. So let’s get to it! (1/33)
First, as everyone can read in wikipedia or a high-school level biology book, cholesterol is used to make many things. It’s a good building block for certain hormones, cell membranes and bile acids. But why? (2/33)
The reason is this sturdy multi-ring structure that has many “corners” for attaching stuff. Depending on specific needs, different types of molecular side chains can be attached to this basic frame (3/33)
